Parasvi S Patel

Parasvi S Patel

University of Toronto

H-index: 10

North America-Canada

About Parasvi S Patel

Parasvi S Patel, With an exceptional h-index of 10 and a recent h-index of 9 (since 2020), a distinguished researcher at University of Toronto, specializes in the field of R-loops, Metastasis, DNA damage, Genome stability.

His recent articles reflect a diverse array of research interests and contributions to the field:

Abstract LB449: Strategies to overcome resistance to PI3Kalpha-selective inhibitors mediated by acquired alterations in the PI3K/AKT pathway

Abstract LB366: KRASG12C inhibition enhances immunogenicity in KRASG12C-mutant colorectal cancer

Unprocessed genomic uracil as a source of DNA replication stress in cancer cells

APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability

ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy

The RNA m5C modification in R-loops as an off switch of Alt-NHEJ

ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms

Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers

Parasvi S Patel Information

University

Position

/ Princess Margaret Cancer Centre

Citations(all)

753

Citations(since 2020)

725

Cited By

220

hIndex(all)

10

hIndex(since 2020)

9

i10Index(all)

10

i10Index(since 2020)

9

Email

University Profile Page

Google Scholar

Parasvi S Patel Skills & Research Interests

R-loops

Metastasis

DNA damage

Genome stability

Top articles of Parasvi S Patel

Abstract LB449: Strategies to overcome resistance to PI3Kalpha-selective inhibitors mediated by acquired alterations in the PI3K/AKT pathway

Cancer Research

2024/4/5

Abstract LB366: KRASG12C inhibition enhances immunogenicity in KRASG12C-mutant colorectal cancer

Cancer Research

2024/4/5

Unprocessed genomic uracil as a source of DNA replication stress in cancer cells

bioRxiv

2024

Sneha Saxena
Sneha Saxena

H-Index: 4

Parasvi S Patel
Parasvi S Patel

H-Index: 6

APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability

Science Advances

2024/1/19

Parasvi S Patel
Parasvi S Patel

H-Index: 6

Sneha Saxena
Sneha Saxena

H-Index: 4

ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy

Genes & Development

2023/10/1

The RNA m5C modification in R-loops as an off switch of Alt-NHEJ

Nature Communications

2023/9/30

ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms

Cell reports

2023/7/25

Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers

Nucleic Acids Research

2023/5/22

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells

Nucleic Acids Research

2023/10/27

The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness

Blood

2020/11/5

Emerging roles of DNA topoisomerases in the regulation of R-loops

2022/4/1

Parasvi S Patel
Parasvi S Patel

H-Index: 6

Rehna Krishnan
Rehna Krishnan

H-Index: 4

Exploiting synthetic lethality to target BRCA1/2-deficient tumors: where we stand

2021/4/29

Parasvi S Patel
Parasvi S Patel

H-Index: 6

Arash Algouneh
Arash Algouneh

H-Index: 2

RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors

The Journal of clinical investigation

2021/2/3

The Role of RNF168 and Novel Genetic Vulnerabilities in BRCA1/2-Mutant Cancers

2021

Parasvi S Patel
Parasvi S Patel

H-Index: 6

BRCA1 and Metastasis: Outcome of Defective DNA Repair

2021/12/27

Rehna Krishnan
Rehna Krishnan

H-Index: 4

Parasvi S Patel
Parasvi S Patel

H-Index: 6

Strategic Training in Transdisciplinary Radiation Science for the 21st Century (STARS21): 5-Year Prospective Evaluation of an Innovative Curriculum in Radiation Science

International Journal of Radiation Oncology, Biology, Physics

2021/11/1

118: Strategic Training in Transdisciplinary Radiation Science for the 21st Century (STARS21): Five-Year Prospective Evaluation of an Innovative Curriculum in Radiation Research

Radiotherapy and Oncology

2021/10/1

Leukemia stem cells demonstrate enhanced DNA damage repair and chemoresistance in AML

Cancer Research

2021/7/1

Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis

The Journal of Clinical Investigation

2021/7/1

Leukemia Stem Cells Demonstrate Increased DNA Damage Repair and Chemoresistance in Acute Myeloid Leukemia

Blood

2020/11/5

See List of Professors in Parasvi S Patel University(University of Toronto)