Leggy A Arnold

Leggy A Arnold

University of Wisconsin-Milwaukee

H-index: 37

North America-United States

About Leggy A Arnold

Leggy A Arnold, With an exceptional h-index of 37 and a recent h-index of 22 (since 2020), a distinguished researcher at University of Wisconsin-Milwaukee, specializes in the field of Drug Discovery, Medicinal Chemistry, Chemical Biology, Molecular Biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Development of A Novel Oral Treatment for Atopic Dermatitis

New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High …

Modulating vitamin D receptor–coregulator binding with small molecules

Development and validation of an LC–MS/MS method for the determination of ARN14988, an acid ceramidase inhibitor, and its application to a pharmacokinetic study in a mouse model

Structural analogs of the GABAkine (5-(8-ethynyl-6-(pyridin-2-yl)-4H-benzo [f] imidazole [1, 5-α][1, 4] diazepin-3-yl) oxazole)(KRM-II-81) are orally bioavailable …

Oral and inhaled fosamprenavir reverses pepsin‐induced damage in a laryngopharyngeal reflux mouse model

Augmentation of Anaerobic Pentose Phosphate Pathway Dysregulates Tetrahydrobiopterin Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Patients with …

Design, Synthesis, and Biological Evaluation of Novel Spiro Imidazobenzodiazepines to Identify Improved Inhaled Bronchodilators

Leggy A Arnold Information

University

Position

Professor of Chemistry and Biochemistry

Citations(all)

6033

Citations(since 2020)

1542

Cited By

4797

hIndex(all)

37

hIndex(since 2020)

22

i10Index(all)

79

i10Index(since 2020)

49

Email

University Profile Page

Google Scholar

Leggy A Arnold Skills & Research Interests

Drug Discovery

Medicinal Chemistry

Chemical Biology

Molecular Biology

Top articles of Leggy A Arnold

Development of A Novel Oral Treatment for Atopic Dermatitis

Journal of Allergy and Clinical Immunology

2024/2/1

New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High …

ACS Chemical Neuroscience

2024/1/4

Modulating vitamin D receptor–coregulator binding with small molecules

2024/1/1

Leggy A Arnold
Leggy A Arnold

H-Index: 20

Development and validation of an LC–MS/MS method for the determination of ARN14988, an acid ceramidase inhibitor, and its application to a pharmacokinetic study in a mouse model

Talanta

2019/11/1

Structural analogs of the GABAkine (5-(8-ethynyl-6-(pyridin-2-yl)-4H-benzo [f] imidazole [1, 5-α][1, 4] diazepin-3-yl) oxazole)(KRM-II-81) are orally bioavailable …

Journal of Pharmacology and Experimental Therapeutics

2023/1/1

Oral and inhaled fosamprenavir reverses pepsin‐induced damage in a laryngopharyngeal reflux mouse model

The Laryngoscope

2023/1

Augmentation of Anaerobic Pentose Phosphate Pathway Dysregulates Tetrahydrobiopterin Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Patients with …

2023/12/11

Daniel Peterson
Daniel Peterson

H-Index: 20

Leggy A Arnold
Leggy A Arnold

H-Index: 20

Design, Synthesis, and Biological Evaluation of Novel Spiro Imidazobenzodiazepines to Identify Improved Inhaled Bronchodilators

Future Journal of Pharmaceutical Sciences

2015/6/1

Comparative anticonvulsant activity of the GABAkine KRM‐II‐81 and a deuterated analog

Drug development research

2023/5

Structural analogs of the GABAkine KRM-II-81 are orally bioavailable anticonvulsants without sedation

Journal of Pharmacology and Experimental Therapeutics

2023/4/1

Gaba (a) receptor modulators and methods to control airway hyperresponsiveness and inflammation in asthma

2023/3/30

Improved 2-pyridyl reductive homocoupling reaction using biorenewable solvent Cyrene™(dihydrolevoglucosenone)

RSC sustainability

2023

Peng Gao
Peng Gao

H-Index: 8

Leggy A Arnold
Leggy A Arnold

H-Index: 20

Imidazobenzodiazepine PI320 Relaxes Mouse Peripheral Airways by Inhibiting Calcium Mobilization

American Journal of Respiratory Cell and Molecular Biology

2022/10

Leggy A Arnold
Leggy A Arnold

H-Index: 20

Substituted benzo [f] imidazo [1, 5-a][1, 4] diazepines as GABA (a) receptor modulators

2022/9/20

Comparative pharmacodynamic and pharmacokinetic study of MIDD0301 and its (S) enantiomer

Drug development research

2022/6

Ms Rashid Roni
Ms Rashid Roni

H-Index: 3

Leggy A Arnold
Leggy A Arnold

H-Index: 20

The Mechanism of Novel Benzodiazepine PI320-Mediated Airway Relaxation in Mouse Lung Slice

2022/5

Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors In Vivo

Journal of medicinal chemistry

2022/4/11

Design, synthesis, and characterization of novel analogs of clinically progressing gamma-aminobutyric acid type A (GABAA) receptor u03b12/u03b13 subtype …

American Chemical Society SciMeetings

2022/3/17

Development of a novel, small-molecule brain-penetrant histone deacetylase inhibitor that enhances spatial memory formation in mice

Journal of medicinal chemistry

2022/2/8

Development of Inhaled GABAA Receptor Modulators to Improve Airway Function in Bronchoconstrictive Disorders

ACS Pharmacology & Translational Science

2022/2/1

Ms Rashid Roni
Ms Rashid Roni

H-Index: 3

Leggy A Arnold
Leggy A Arnold

H-Index: 20

See List of Professors in Leggy A Arnold University(University of Wisconsin-Milwaukee)

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