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Grant Challen

Grant Challen

Washington University in St. Louis

H-index: 32

North America-United States

Contact Grant Challen

About Grant Challen

Grant Challen, With an exceptional h-index of 32 and a recent h-index of 28 (since 2020), a distinguished researcher at Washington University in St. Louis, specializes in the field of stem cells, epigenetics.

His recent articles reflect a diverse array of research interests and contributions to the field:

Enhanced Molecular Response in Myeloproliferative Neoplasms with Complete JAK2V617F Inhibition

Engineering a humanized animal model of polycythemia vera with minimal JAK2V617F mutant allelic burden

Spatial Mapping of Hematopoietic Clones in Human Bone Marrow

Inactivation of DNA Polymerase Theta (PolΘ) Is Synthetic Lethal in DNMT3A Mutated Myeloid Malignancies-Potential Clinical Applications

Leukemic Driver Clones Can Arise Independently and Outcompete MPN Cells in Post-MPN Secondary AML

The Tetraspanin CD53 Promotes the Clonal Advantage of Dnmt3a-Deficient Hematopoietic Stem Cells

Methods to Elucidate Hematopoietic Clonal Organization in Bone Marrow

Stathmin-1 Regulates Hematopoietic Stem Cell Mitochondrial and Cellular Function

Grant Challen Information

University

Position

School of Medicine

Citations(all)

7432

Citations(since 2020)

3922

Cited By

4931

hIndex(all)

32

hIndex(since 2020)

28

i10Index(all)

47

i10Index(since 2020)

42

Email

University Profile Page

Google Scholar

Grant Challen Skills & Research Interests

stem cells

epigenetics

Top articles of Grant Challen

Enhanced Molecular Response in Myeloproliferative Neoplasms with Complete JAK2V617F Inhibition

Cancer Discovery

2024/5/1

Hamza Celik
Hamza Celik

H-Index: 11

Engineering a humanized animal model of polycythemia vera with minimal JAK2V617F mutant allelic burden

Haematologica

2024/3/3

Spatial Mapping of Hematopoietic Clones in Human Bone Marrow

Blood Cancer Discovery

2024/2/29

Lulu Sun
Lulu Sun

H-Index: 5

Inactivation of DNA Polymerase Theta (PolΘ) Is Synthetic Lethal in DNMT3A Mutated Myeloid Malignancies-Potential Clinical Applications

Blood

2023/11/28

Monika Toma
Monika Toma

H-Index: 15

Emir Hadzijusufovic
Emir Hadzijusufovic

H-Index: 20

Peter Valent
Peter Valent

H-Index: 5

Jean-Yves Masson
Jean-Yves Masson

H-Index: 36

Leukemic Driver Clones Can Arise Independently and Outcompete MPN Cells in Post-MPN Secondary AML

Blood

2023/11/28

The Tetraspanin CD53 Promotes the Clonal Advantage of Dnmt3a-Deficient Hematopoietic Stem Cells

Blood

2023/11/28

Mousumi Chakraborty
Mousumi Chakraborty

H-Index: 19

Qian Dong
Qian Dong

H-Index: 1

Methods to Elucidate Hematopoietic Clonal Organization in Bone Marrow

Blood

2023/11/28

Stathmin-1 Regulates Hematopoietic Stem Cell Mitochondrial and Cellular Function

Blood

2023/11/28

Qian Dong
Qian Dong

H-Index: 1

Mousumi Chakraborty
Mousumi Chakraborty

H-Index: 19

Cliff Luke
Cliff Luke

H-Index: 14

Understanding the Functional Differences between PRC2. 1 and PRC2. 2 in Hematopoiesis

Blood

2023/11/28

Yanan Li
Yanan Li

H-Index: 1

Wei Yang
Wei Yang

H-Index: 22

RSK1 Is an Exploitable Dependency in Myeloid Malignancies

Blood

2023/11/2

Tim Kong
Tim Kong

H-Index: 6

Wei Yang
Wei Yang

H-Index: 22

Fan He
Fan He

H-Index: 8

KDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress

Leukemia

2023/4

3056–DNMT3A MUTATIONS UPREGULATE CELL ADHESION MOLECULES TO PROMOTE INVASIVENESS OF T-ALL CELLS

Experimental Hematology

2023/1/1

Andrew Young
Andrew Young

H-Index: 25

Grant Challen
Grant Challen

H-Index: 21

3077–JARID2-MEDIATED EPIGENETIC REPROGRAMMING OF HUMAN HEMATOPOIETIC PROGENITORS FOR STEM CELL TRANSPLANTATION

Experimental Hematology

2023/1/1

Hamza Celik
Hamza Celik

H-Index: 11

Andrew Young
Andrew Young

H-Index: 25

Grant Challen
Grant Challen

H-Index: 21

3225–DNA METHYLATION-INDEPENDENT FUNCTIONS OF DNMT3A REGULATE HEMATOPOIETIC STEM CELL FUNCTION

Experimental Hematology

2023/1/1

Won Kyun Koh
Won Kyun Koh

H-Index: 5

Andrew Young
Andrew Young

H-Index: 25

Ting Wang
Ting Wang

H-Index: 6

Grant Challen
Grant Challen

H-Index: 21

DUSP6 mediates resistance to JAK2 inhibition and drives leukemic progression

Nature Cancer

2023/1

Tim Kong
Tim Kong

H-Index: 6

Kangning Yang
Kangning Yang

H-Index: 1

Hamza Celik
Hamza Celik

H-Index: 11

Sidong Huang
Sidong Huang

H-Index: 19

Droplet Digital PCR for Oncogenic KMT2A Fusion Detection

The Journal of Molecular Diagnostics

2023/12/1

Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis

Cancer discovery

2022/12/2

The Role of Stathmin-1 in the Regulation of Hematopoietic Stem Cells

Blood

2022/11/15

Qian Dong
Qian Dong

H-Index: 1

Cliff Luke
Cliff Luke

H-Index: 14

Using a Humanized Animal Model to Determine the Minimum JAK2V617F Mutant Allele Burden Required to Generate MPN Pathologies

Blood

2022/11/15

Dnmt3a Loss-of-Function Enhances DNA Repair in Proliferative HSCs Under Inflammatory Stress

Blood

2022/11/15

See List of Professors in Grant Challen University(Washington University in St. Louis)