Gopinath Krishnan
University of Massachusetts Medical School
H-index: 14
North America-United States
Top articles of Gopinath Krishnan
Traumatic injury causes selective degeneration and TDP-43 mislocalization in human iPSC-derived C9orf72-associated ALS/FTD motor neurons
bioRxiv
2024
Gopinath Krishnan
H-Index: 9
Evangelos Kiskinis
H-Index: 23
Translation of dipeptide repeat proteins in C9ORF72 ALS/FTD through unique and redundant AUG initiation codons
Elife
2023/9/7
Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly (GR)-induced neurotoxicity in C9ORF72-ALS/FTD
Neuron
2023/5/3
Soojin Lee
H-Index: 11
Yong-Woo Jun
H-Index: 6
Brandon Butler
H-Index: 1
Gopinath Krishnan
H-Index: 9
Neal Silverman
H-Index: 36
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS
Cell
2023/2/16
The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias
Acta Neuropathologica Communications
2022/11/22
Yongping Chen
H-Index: 31
Gopinath Krishnan
H-Index: 9
Sepideh Parsi
H-Index: 6
Lu Cao
H-Index: 1
Zuoshang Xu
H-Index: 42
CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro
Nature communications
2022/10/21
Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD
Nature communications
2022/5/19
Gopinath Krishnan
H-Index: 9
A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation
Nature communications
2021/10/15
Gopinath Krishnan
H-Index: 9
Priota Islam
H-Index: 3
Evangelos Kiskinis
H-Index: 23
Paschalis Kratsios
H-Index: 13
Altered MICOS morphology and mitochondrial ion homeostasis contribute to poly (GR) toxicity associated with C9-ALS/FTD
Cell reports
2020/8/4
CRISPR deletion of the C9ORF72 promoter in ALS/FTD patient motor neurons abolishes production of dipeptide repeat proteins and rescues neurodegeneration
Acta neuropathologica
2020/7
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J. Chem. Theory Comput
2017
