David Christianson

David Christianson

University of Pennsylvania

H-index: 94

North America-United States

About David Christianson

David Christianson, With an exceptional h-index of 94 and a recent h-index of 43 (since 2020), a distinguished researcher at University of Pennsylvania, specializes in the field of biochemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

Structure of the prenyltransferase in bifunctional copalyl diphosphate synthase from Penicillium fellutanum reveals an open hexamer conformation

Structure-Based Engineering of a Sesquiterpene Cyclase to Generate an Alcohol Product: Conversion of epi-Isozizaene Synthase into α-Bisabolol Synthase

Methods for the preparation and analysis of a bifunctional class II diterpene synthase, copalyl diphosphate synthase from Penicillium fellutanum

Methods for the preparation and analysis of the diterpene cyclase fusicoccadiene synthase

Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation

Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6

Crystal structure of histone deacetylase 6 complexed with (R)-lipoic acid, an essential cofactor in central carbon metabolism

Structure and Function of Kdac1, a Class II Deacetylase from the Multidrug-Resistant Pathogen Acinetobacter baumannii

David Christianson Information

University

Position

Professor of Chemistry

Citations(all)

27731

Citations(since 2020)

7758

Cited By

22761

hIndex(all)

94

hIndex(since 2020)

43

i10Index(all)

248

i10Index(since 2020)

174

Email

University Profile Page

Google Scholar

David Christianson Skills & Research Interests

biochemistry

Top articles of David Christianson

Structure of the prenyltransferase in bifunctional copalyl diphosphate synthase from Penicillium fellutanum reveals an open hexamer conformation

Journal of Structural Biology

2024/3/1

Structure-Based Engineering of a Sesquiterpene Cyclase to Generate an Alcohol Product: Conversion of epi-Isozizaene Synthase into α-Bisabolol Synthase

Biochemistry

2024/2/29

Methods for the preparation and analysis of a bifunctional class II diterpene synthase, copalyl diphosphate synthase from Penicillium fellutanum

2024/1/16

Methods for the preparation and analysis of the diterpene cyclase fusicoccadiene synthase

2023/12/8

Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation

Journal of Medicinal Chemistry

2023/10/30

Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6

Journal of Medicinal Chemistry

2023/10/2

Crystal structure of histone deacetylase 6 complexed with (R)-lipoic acid, an essential cofactor in central carbon metabolism

Journal of Biological Chemistry

2023/10/1

Structure and Function of Kdac1, a Class II Deacetylase from the Multidrug-Resistant Pathogen Acinetobacter baumannii

Biochemistry

2023/8/25

Reprogramming the Cyclization Cascade of epi-Isozizaene Synthase to Generate Alternative Terpene Products

Biochemistry

2023/7/14

Macrocyclic octapeptide binding and inferences on protein substrate binding to histone deacetylase 6

ACS Chemical Biology

2023/4/7

Development of fluorinated peptoid-based histone deacetylase (HDAC) inhibitors for therapy-resistant acute leukemia

Journal of medicinal chemistry

2022/11/9

Transient prenyltransferase–cyclase association in fusicoccadiene synthase, an assembly-line terpene synthase

Biochemistry

2022/10/13

Aza-SAHA derivatives are selective histone deacetylase 10 chemical probes that inhibit polyamine deacetylation and phenocopy HDAC10 knockout

Journal of the American Chemical Society

2022/10/6

Structural Basis of Substrate Promiscuity and Catalysis by the Reverse Prenyltransferase N-Dimethylallyl-l-tryptophan Synthase from Fusarium fujikuroi

Biochemistry

2022/9/9

Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6

Biochemistry

2022/9/8

Structure of the Repurposed Fungal Terpene Cyclase FlvF Implicated in the C–N Bond-Forming Reaction of Flavunoidine Biosynthesis

Biochemistry

2022/8/29

First fluorescent acetylspermidine deacetylation assay for HDAC10 identifies selective inhibitors with cellular target engagement

ChemBioChem

2022/7/19

Structural Analysis of a Non‐canonical Terpene Synthase

The FASEB Journal

2022/5

Assembly‐line catalysis in bifunctional terpene synthases: (+)‐Copalyl diphosphate synthase from fungal Penicillium species

The FASEB Journal

2022/5

A Novel Zinc Binding Group for HDAC6 Inhibition

The FASEB Journal

2022/5

See List of Professors in David Christianson University(University of Pennsylvania)