David Christianson
University of Pennsylvania
H-index: 94
North America-United States
Top articles of David Christianson
Structure of the prenyltransferase in bifunctional copalyl diphosphate synthase from Penicillium fellutanum reveals an open hexamer conformation
Journal of Structural Biology
2024/3/1
Structure-Based Engineering of a Sesquiterpene Cyclase to Generate an Alcohol Product: Conversion of epi-Isozizaene Synthase into α-Bisabolol Synthase
Biochemistry
2024/2/29
Methods for the preparation and analysis of a bifunctional class II diterpene synthase, copalyl diphosphate synthase from Penicillium fellutanum
2024/1/16
Methods for the preparation and analysis of the diterpene cyclase fusicoccadiene synthase
2023/12/8
Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation
Journal of Medicinal Chemistry
2023/10/30
Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6
Journal of Medicinal Chemistry
2023/10/2
Crystal structure of histone deacetylase 6 complexed with (R)-lipoic acid, an essential cofactor in central carbon metabolism
Journal of Biological Chemistry
2023/10/1
Structure and Function of Kdac1, a Class II Deacetylase from the Multidrug-Resistant Pathogen Acinetobacter baumannii
Biochemistry
2023/8/25
Reprogramming the Cyclization Cascade of epi-Isozizaene Synthase to Generate Alternative Terpene Products
Biochemistry
2023/7/14
Macrocyclic octapeptide binding and inferences on protein substrate binding to histone deacetylase 6
ACS Chemical Biology
2023/4/7
Development of fluorinated peptoid-based histone deacetylase (HDAC) inhibitors for therapy-resistant acute leukemia
Journal of medicinal chemistry
2022/11/9
Transient prenyltransferase–cyclase association in fusicoccadiene synthase, an assembly-line terpene synthase
Biochemistry
2022/10/13
Aza-SAHA derivatives are selective histone deacetylase 10 chemical probes that inhibit polyamine deacetylation and phenocopy HDAC10 knockout
Journal of the American Chemical Society
2022/10/6
Structural Basis of Substrate Promiscuity and Catalysis by the Reverse Prenyltransferase N-Dimethylallyl-l-tryptophan Synthase from Fusarium fujikuroi
Biochemistry
2022/9/9
Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6
Biochemistry
2022/9/8
Structure of the Repurposed Fungal Terpene Cyclase FlvF Implicated in the C–N Bond-Forming Reaction of Flavunoidine Biosynthesis
Biochemistry
2022/8/29
First fluorescent acetylspermidine deacetylation assay for HDAC10 identifies selective inhibitors with cellular target engagement
ChemBioChem
2022/7/19
Assembly‐line catalysis in bifunctional terpene synthases: (+)‐Copalyl diphosphate synthase from fungal Penicillium species
The FASEB Journal
2022/5
A Novel Zinc Binding Group for HDAC6 Inhibition
The FASEB Journal
2022/5