Anthony Fehr

Anthony Fehr

University of Kansas

H-index: 31

North America-United States

About Anthony Fehr

Anthony Fehr, With an exceptional h-index of 31 and a recent h-index of 25 (since 2020), a distinguished researcher at University of Kansas, specializes in the field of Virology.

His recent articles reflect a diverse array of research interests and contributions to the field:

SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling

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Mutation of highly conserved residues in loop 2 of the coronavirus macrodomain demonstrates that enhanced ADP-ribose binding is detrimental to infection

PARP14 is pro-and anti-viral host factor that promotes IFN production and affects the replication of multiple viruses

An Update on the Current State of SARS-CoV-2 Mac1 Inhibitors

PARP12 is required to repress the replication of a Mac1 mutant coronavirus in a cell-and tissue-specific manner

Discovery of 2-amide-3-methylester thiophenes that target SARS-CoV-2 Mac1 and repress coronavirus replication, validating Mac1 as an anti-viral target

SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice

Anthony Fehr Information

University

Position

Assistant Professor

Citations(all)

10594

Citations(since 2020)

9906

Cited By

5142

hIndex(all)

31

hIndex(since 2020)

25

i10Index(all)

41

i10Index(since 2020)

40

Email

University Profile Page

Google Scholar

Anthony Fehr Skills & Research Interests

Virology

Top articles of Anthony Fehr

SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling

Proceedings of the National Academy of Sciences

2024/4/9

Mutation of highly conserved residues in loop 2 of the coronavirus macrodomain demonstrates that enhanced ADP-ribose binding is detrimental to infection

bioRxiv

2024/1/4

PARP14 is pro-and anti-viral host factor that promotes IFN production and affects the replication of multiple viruses

bioRxiv

2024

David Davido
David Davido

H-Index: 10

Anthony Fehr
Anthony Fehr

H-Index: 22

An Update on the Current State of SARS-CoV-2 Mac1 Inhibitors

2023/10/7

PARP12 is required to repress the replication of a Mac1 mutant coronavirus in a cell-and tissue-specific manner

Journal of Virology

2023/9/28

Discovery of 2-amide-3-methylester thiophenes that target SARS-CoV-2 Mac1 and repress coronavirus replication, validating Mac1 as an anti-viral target

bioRxiv

2023/8/29

SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice

Proceedings of the National Academy of Sciences

2023/8/29

Two Commercially Available Blood-Stabilization Reagents Serve as Potent Inactivators of Coronaviruses

Pathogens

2023/8/25

Inhibitors of One or More Cellular Aurora Kinases Impair the Replication of Herpes Simplex Virus 1 and Other DNA and RNA Viruses with Diverse Genomes and Life Cycles

Microbiology Spectrum

2023/2/14

Discovery of 2-amide-3-methylester thiophenes inhibiting SARS-CoV-2 ADP-ribosyl hydrolysing macrodomain and coronavirus replication (preprint)

2023

Anthony Fehr
Anthony Fehr

H-Index: 22

Design, synthesis and evaluation of inhibitors of the SARS-CoV-2 nsp3 macrodomain

Bioorganic & Medicinal Chemistry

2022/8/1

Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening

Antiviral Research

2022/7/1

PARP14: a key ADP-ribosylating protein in host–virus interactions?

2022/6/9

MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells

Proceedings of the National Academy of Sciences

2022/5/24

Reviewer 1:" A bacterial artificial chromosome (BAC)-vectored noninfectious replicon of SARS-CoV-2"

Rapid Reviews Infectious Diseases

2022/4/13

Anthony Fehr
Anthony Fehr

H-Index: 22

The Conserved Macrodomain Is a Potential Therapeutic Target for Coronaviruses and Alphaviruses. Pathogens 2022, 11, 94

2022

High-throughput activity assay for screening inhibitors of the SARS-CoV-2 Mac1 macrodomain

ACS chemical biology

2021/12/14

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