Adrian Saurin

The search for CDK4/6 inhibitor biomarkers has been hampered by inappropriate proliferation assays

Design and Validation of Flim-timer for Measuring Protein Turnover in Cells Using Fluorescence Lifetime

CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence

Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest

A bifunctional kinase–phosphatase module balances mitotic checkpoint strength and kinetochore–microtubule attachment stability

Cell overgrowth during G1 arrest triggers an osmotic stress response and chronic p38 activation to promote cell cycle exit

A bifunctional kinase-phosphatase module integrates mitotic checkpoint and error-correction signalling to ensure mitotic fidelity

CDK4/6 inhibitors induce replication stress to cause long‐term cell cycle withdrawal