Zacharias Faidon Brotzakis

Discovery of the First‐in‐Class Inhibitors of Hypoxia Up‐Regulated Protein 1 (HYOU1) Suppressing Pathogenic Fibroblast Activation

Cryo-electron Microscopy and Molecular Modeling Methods to Characterize the Dynamics of Tau Bound to Microtubules

Where cryo-electron and computational microscopy converge: The story of the elusive flipback conformation of protein kinase A and its critical role in phosphodiesterase cyclic …

Using Generative Modeling to Endow with Potency Initially Inert Compounds with Good Bioavailability and Low Toxicity

Small molecules targeting the structural dynamics of AR-V7 partially disordered protein using deep learning and physics based models

Transient interactions between the fuzzy coat and the cross-β core of brain-derived Aβ42 filaments

Discovery of potent inhibitors of α-Synuclein aggregation using structure-based iterative learning

Multiplexed Digital Characterization of Misfolded Protein Oligomers via Solid-State Nanopores