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Xin Han

Xin Han

University of Michigan

H-index: 18

North America-United States

Contact Xin Han

About Xin Han

Xin Han, With an exceptional h-index of 18 and a recent h-index of 15 (since 2020), a distinguished researcher at University of Michigan, specializes in the field of medicinal chemistry, drug discovery, chemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

Corrigendum to “Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment”[Neoplasia, Volume 22, Issue 2 (2020) 111–119]

Androgen receptor protein degraders with a tricyclic cereblon ligand

Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR+ Human Prostate Cancer

Small molecule androgen receptor protein degraders

Androgen receptor protein degraders

Discovery of ARD-2051 as a potent and orally efficacious proteolysis targeting chimera (PROTAC) degrader of androgen receptor for the treatment of advanced prostate cancer

PROTACs: A novel strategy for cancer drug discovery and development

Targeting androgen receptor degradation with PROTACs from bench to bedside

Xin Han Information

University

Position

___

Citations(all)

1577

Citations(since 2020)

1262

Cited By

716

hIndex(all)

18

hIndex(since 2020)

15

i10Index(all)

21

i10Index(since 2020)

18

Email

University Profile Page

Google Scholar

Xin Han Skills & Research Interests

medicinal chemistry

drug discovery

chemistry

Top articles of Xin Han

Corrigendum to “Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment”[Neoplasia, Volume 22, Issue 2 (2020) 111–119]

Neoplasia (New York, NY)

2024/5

Steven Kregel
Steven Kregel

H-Index: 13

Chao Wang
Chao Wang

H-Index: 6

Xin Han
Xin Han

H-Index: 13

Lanbo Xiao
Lanbo Xiao

H-Index: 22

Pushpinder Bawa
Pushpinder Bawa

H-Index: 6

Shaomeng Wang
Shaomeng Wang

H-Index: 52

Androgen receptor protein degraders with a tricyclic cereblon ligand

2023/11/9

Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR+ Human Prostate Cancer

Journal of Medicinal Chemistry

2023/9/8

Xin Han
Xin Han

H-Index: 13

Tianfeng Xu
Tianfeng Xu

H-Index: 10

Steven Kregel
Steven Kregel

H-Index: 13

Mi Wang
Mi Wang

H-Index: 11

Chong Qin
Chong Qin

H-Index: 13

Mingliang Wang
Mingliang Wang

H-Index: 9

Lu Wang
Lu Wang

H-Index: 6

Bo Wen
Bo Wen

H-Index: 16

Shaomeng Wang
Shaomeng Wang

H-Index: 52

Small molecule androgen receptor protein degraders

2023/8/17

Androgen receptor protein degraders

2023/7/27

Discovery of ARD-2051 as a potent and orally efficacious proteolysis targeting chimera (PROTAC) degrader of androgen receptor for the treatment of advanced prostate cancer

Journal of Medicinal Chemistry

2023/6/29

Xin Han
Xin Han

H-Index: 13

Chong Qin
Chong Qin

H-Index: 13

Mi Wang
Mi Wang

H-Index: 11

Tianfeng Xu
Tianfeng Xu

H-Index: 10

Yu Wang
Yu Wang

H-Index: 14

Lu Wang
Lu Wang

H-Index: 6

Bo Wen
Bo Wen

H-Index: 16

Shaomeng Wang
Shaomeng Wang

H-Index: 52

PROTACs: A novel strategy for cancer drug discovery and development

2023/6

Xin Han
Xin Han

H-Index: 13

Yi Sun
Yi Sun

H-Index: 2

Targeting androgen receptor degradation with PROTACs from bench to bedside

2023/2/1

Xin Han
Xin Han

H-Index: 13

Mdm2 protein degraders

2022/12/29

Recent Advances in Targeting the Androgen Receptor with Protacs

2022/12/21

Xin Han
Xin Han

H-Index: 13

Shaomeng Wang
Shaomeng Wang

H-Index: 52

Spirocyclic androgen receptor protein degraders

2022/12/1

Strategies for the discovery of oral PROTAC degraders aimed at cancer therapy

2022/10/19

Xin Han
Xin Han

H-Index: 13

Yi Sun
Yi Sun

H-Index: 2

PROTAC degraders with ligands recruiting MDM2 E3 ubiquitin ligase: an updated perspective

2022

Xin Han
Xin Han

H-Index: 13

Wenyi Wei
Wenyi Wei

H-Index: 52

Yi Sun
Yi Sun

H-Index: 2

Discovery of ARD-2585 as an exceptionally potent and orally active PROTAC degrader of androgen receptor for the treatment of advanced prostate cancer

Journal of medicinal chemistry

2021/9/2

Xin Han
Xin Han

H-Index: 13

Chong Qin
Chong Qin

H-Index: 13

Yu Wang
Yu Wang

H-Index: 14

Lu Wang
Lu Wang

H-Index: 6

Miao He
Miao He

H-Index: 7

Bo Wen
Bo Wen

H-Index: 16

Shaomeng Wang
Shaomeng Wang

H-Index: 52

Monofunctional intermediates for ligand-dependent target protein degradation

2021/1/7

A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo

Neoplasia

2020/10/1

Xin Han
Xin Han

H-Index: 13

Shaomeng Wang
Shaomeng Wang

H-Index: 52

Targeted androgen receptor (AR) protein degradation for the treatment of metastatic castration-resistant prostate cancer (mCRPC)

Cancer Research

2020/8/15

Xin Han
Xin Han

H-Index: 13

Chong Qin
Chong Qin

H-Index: 13

Tianfeng Xu
Tianfeng Xu

H-Index: 10

Mi Wang
Mi Wang

H-Index: 11

Shaomeng Wang
Shaomeng Wang

H-Index: 52

Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment

Neoplasia

2020/2/1

Steven Kregel
Steven Kregel

H-Index: 13

Chao Wang
Chao Wang

H-Index: 6

Xin Han
Xin Han

H-Index: 13

Lanbo Xiao
Lanbo Xiao

H-Index: 22

Pushpinder Bawa
Pushpinder Bawa

H-Index: 6

Shaomeng Wang
Shaomeng Wang

H-Index: 52

See List of Professors in Xin Han University(University of Michigan)