Vedagopuram Sreekanth

Vedagopuram Sreekanth

Harvard University

H-index: 14

North America-United States

About Vedagopuram Sreekanth

Vedagopuram Sreekanth, With an exceptional h-index of 14 and a recent h-index of 11 (since 2020), a distinguished researcher at Harvard University, specializes in the field of Chemical Biology, CRISPR-Cas, Diabetes/Sc-βcells, Cancer-Pharmacology, Drug/Protein/Nucleic acid delivery.

His recent articles reflect a diverse array of research interests and contributions to the field:

Proteolysis-targeting chimeras with reduced off-targets

Inhibitors of RNA-guided nucleases and uses thereof

Continuous evolution of compact protein degradation tags regulated by selective molecular glues

Small molecules that disrupt RAD54-BLM interaction hamper tumor proliferation in colon cancer chemoresistance models

FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity

Photoswitchable Molecular Glues Enable Optical Control of Transcription Factor Degradation

A molecular glue approach to control the half-life of CRISPR-based technologies

Identifying anti-CRISPR small molecules via high-throughput assay

Vedagopuram Sreekanth Information

University

Position

Postdoctoral Research Fellow: Brigham & Women's Hospital, Harvard Medical School, Broad Institute

Citations(all)

532

Citations(since 2020)

351

Cited By

304

hIndex(all)

14

hIndex(since 2020)

11

i10Index(all)

18

i10Index(since 2020)

13

Email

University Profile Page

Google Scholar

Vedagopuram Sreekanth Skills & Research Interests

Chemical Biology

CRISPR-Cas

Diabetes/Sc-βcells

Cancer-Pharmacology

Drug/Protein/Nucleic acid delivery

Top articles of Vedagopuram Sreekanth

Inhibitors of RNA-guided nucleases and uses thereof

2023/10/17

Continuous evolution of compact protein degradation tags regulated by selective molecular glues

Science

2024/3/15

Small molecules that disrupt RAD54-BLM interaction hamper tumor proliferation in colon cancer chemoresistance models

The Journal of Clinical Investigation

2024

Photoswitchable Molecular Glues Enable Optical Control of Transcription Factor Degradation

Biorxiv

2023

A molecular glue approach to control the half-life of CRISPR-based technologies

bioRxiv

2023/3/20

Identifying anti-CRISPR small molecules via high-throughput assay

2022/11/17

A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules

Nature cell biology

2022/12

CRISPR-based therapeutics: current challenges and future applications

Trends in Pharmacological Sciences

2022

Zinc finger degradation domains

2023/5/18

Self-assembled Supramolecular Nanomicelles from Bile Acid-Docetaxel Conjugate are Highly Tolerable with Improved Therapeutic Efficacy

Biomaterials Science

2021

Bile Acid Tethered Docetaxel‐based Nanomicelles Mitigate Tumor Progression through Epigenetic Changes.

Angewandte Chemie International Edition

2021/3/1

Engineering designer beta cells with a CRISPR-Cas9 conjugation platform

Nature communications

2020/8/13

Donghyun Lim
Donghyun Lim

H-Index: 1

Vedagopuram Sreekanth
Vedagopuram Sreekanth

H-Index: 9

Amit Choudhary
Amit Choudhary

H-Index: 5

Novel Nucleic Acid Modifiers

2022/5/26

Methods and Compositions for Cell Therapy

2022/6/9

A 3D culture platform enables development of zinc-binding prodrugs for targeted proliferation of β cells

Science Advances

2020/11/18

Chemogenetic System Demonstrates That Cas9 Longevity Impacts Genome Editing Outcomes

ACS Central Science

2020/11/18

See List of Professors in Vedagopuram Sreekanth University(Harvard University)

Co-Authors

academic-engine