Sheng Tian

About Sheng Tian

Sheng Tian, With an exceptional h-index of 26 and a recent h-index of 21 (since 2020), a distinguished researcher at Soochow University, specializes in the field of Computer-aided drug design, Cheminformatics and Bioinformatics.

His recent articles reflect a diverse array of research interests and contributions to the field:

Prediction of Drug-Induced Liver Injury: From Molecular Physicochemical Properties and Scaffold Architectures to Machine Learning Approaches

Subtle structural alteration in indisulam switches the molecular mechanisms for the inhibitory effect on the migration of gastric cancer cells

Identification of Spiro[chromene-2,4′-piperidine]s as Potent, Selective, and Gq-Biased 5-HT2C Receptor Partial Agonists

Synthesis and evaluation of dihydrofuro [2, 3-b] pyridine derivatives as potent IRAK4 inhibitors

Design, synthesis, evaluation and optimization of potent IRAK4 inhibitors alleviating production of inflammatory cytokines in LPS-induced SIRS model

Structure-based virtual screening for discovery of paederosidic acid from Paederia scandens as novel P2Y14R antagonist

Discovery of STAT3 inhibitors: recent advances and future perspectives

Discovery of Selective P2Y6R Antagonists with High Affinity and In Vivo Efficacy for Inflammatory Disease Therapy

Sheng Tian Information

University

Position

PhD student Institute of Functional Nano & Soft Materials(FUNSOM)

Citations(all)

3902

Citations(since 2020)

2724

Cited By

2296

hIndex(all)

26

hIndex(since 2020)

21

i10Index(all)

40

i10Index(since 2020)

37

Email

University Profile Page

Google Scholar

Sheng Tian Skills & Research Interests

Computer-aided drug design

Cheminformatics and Bioinformatics

Top articles of Sheng Tian

Prediction of Drug-Induced Liver Injury: From Molecular Physicochemical Properties and Scaffold Architectures to Machine Learning Approaches

2024/4/18

Subtle structural alteration in indisulam switches the molecular mechanisms for the inhibitory effect on the migration of gastric cancer cells

Biomedicine & Pharmacotherapy

2024/3/1

Identification of Spiro[chromene-2,4′-piperidine]s as Potent, Selective, and Gq-Biased 5-HT2C Receptor Partial Agonists

ACS Medicinal Chemistry Letters

2023/12/18

Synthesis and evaluation of dihydrofuro [2, 3-b] pyridine derivatives as potent IRAK4 inhibitors

European Journal of Medicinal Chemistry

2023/10/5

Design, synthesis, evaluation and optimization of potent IRAK4 inhibitors alleviating production of inflammatory cytokines in LPS-induced SIRS model

Bioorganic Chemistry

2023/8/1

Structure-based virtual screening for discovery of paederosidic acid from Paederia scandens as novel P2Y14R antagonist

Phytomedicine

2023/7/1

Discovery of STAT3 inhibitors: recent advances and future perspectives

2023/5/1

Jiawei Wang
Jiawei Wang

H-Index: 47

Sheng Tian
Sheng Tian

H-Index: 19

Discovery of Selective P2Y6R Antagonists with High Affinity and In Vivo Efficacy for Inflammatory Disease Therapy

Journal of Medicinal Chemistry

2023/4/20

Predicting the mutation effects of protein–ligand interactions via end-point binding free energy calculations: strategies and analyses

Journal of Cheminformatics

2022/8/20

Structural optimizations and bioevaluation of NH aporphine analogues as Gq-biased and selective serotonin 5-HT2C receptor agonists

Bioorganic Chemistry

2022/6/1

Qi Mao
Qi Mao

H-Index: 3

Sheng Tian
Sheng Tian

H-Index: 19

Discovery of novel MIF inhibitors that attenuate microglial inflammatory activation by structures-based virtual screening and in vitro bioassays

Acta Pharmacologica Sinica

2022/6

GPR105-targeted therapy promotes gout resolution as a switch between NETosis and apoptosis of neutrophils

Frontiers in Immunology

2022/3/30

Synthesis and characterization of potent RIPK3 inhibitors based on a tricyclic scaffold

Future Medicinal Chemistry

2022/3/1

Design, synthesis, and evaluation of potent RIPK1 inhibitors with inávivo anti-inflammatory activity

European Journal of Medicinal Chemistry

2022/1/15

Discovery and computational studies of 2-phenyl-benzoxazole acetamide derivatives as promising P2Y14R antagonists with anti-gout potential

European Journal of Medicinal Chemistry

2022/1/5

Discovery, optimization and evaluation of isothiazolo [5, 4-b] pyridine derivatives as RIPK1 inhibitors with potent in vivo anti-SIRS activity

Bioorganic Chemistry

2022/12/1

Determination of molecule category of ligands targeting the ligand-binding pocket of nuclear receptors with structural elucidation and machine learning

Journal of Chemical Information and Modeling

2022/8/30

Ring closure strategy leads to potent RIPK3 inhibitors

European Journal of Medicinal Chemistry

2021/5/5

Small molecules selectively targeting sigma-1 receptor for the treatment of neurological diseases

2020/10/28

Sheng Tian
Sheng Tian

H-Index: 19

Jia Zhou
Jia Zhou

H-Index: 12

Design, synthesis, and characterization of novel CXCR4 antagonists featuring cyclic amines

ChemMedChem

2020/7/3

See List of Professors in Sheng Tian University(Soochow University)