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Sajid Khan

Sajid Khan

University of Florida

H-index: 20

North America-United States

Contact Sajid Khan

About Sajid Khan

Sajid Khan, With an exceptional h-index of 20 and a recent h-index of 20 (since 2020), a distinguished researcher at University of Florida, specializes in the field of Targeted Protein Degradation, Drug Discovery, Cancer Metastasis, Epigenetics, Obesity and Cancer.

His recent articles reflect a diverse array of research interests and contributions to the field:

DDR-targeting small molecule inhibitor as a novel therapeutic for treating pancreatic ductal adenocarcinoma

Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

Targeting KRAS in pancreatic cancer: Emerging therapeutic strategies

A BCL-XL PROTAC degrader DT2216 synergizes with KRASG12C inhibitors for effectively treating KRASG12C-mutated cancers

BCL-XL PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRASG12C-mutated cancers

BCL-X

Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL–Specific Degrader DT2216

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity

Sajid Khan Information

University

Position

Post-Doctoral Associate at

Citations(all)

1862

Citations(since 2020)

1547

Cited By

676

hIndex(all)

20

hIndex(since 2020)

20

i10Index(all)

27

i10Index(since 2020)

24

Email

University Profile Page

Google Scholar

Sajid Khan Skills & Research Interests

Targeted Protein Degradation

Drug Discovery

Cancer Metastasis

Epigenetics

Obesity and Cancer

Top articles of Sajid Khan

DDR-targeting small molecule inhibitor as a novel therapeutic for treating pancreatic ductal adenocarcinoma

Cancer Research

2023/4/4

Sajid Khan
Sajid Khan

H-Index: 14

Daohong Zhou
Daohong Zhou

H-Index: 37

Matthew Hart
Matthew Hart

H-Index: 4

Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

Cell Death Discovery

2023/1/2

Sajid Khan
Sajid Khan

H-Index: 14

Patrick Kellish
Patrick Kellish

H-Index: 5

Nick Connis
Nick Connis

H-Index: 6

Dinesh Thummuri
Dinesh Thummuri

H-Index: 18

Peiyi Zhang
Peiyi Zhang

H-Index: 5

Xuan Zhang
Xuan Zhang

H-Index: 2

Vivekananda Budamagunta
Vivekananda Budamagunta

H-Index: 4

Nan Hua
Nan Hua

H-Index: 13

Yang Yang
Yang Yang

H-Index: 9

Weizhou Zhang
Weizhou Zhang

H-Index: 32

Guangrong Zheng
Guangrong Zheng

H-Index: 15

Daohong Zhou
Daohong Zhou

H-Index: 37

Targeting KRAS in pancreatic cancer: Emerging therapeutic strategies

2023/1/1

Sajid Khan
Sajid Khan

H-Index: 14

Vivekananda Budamagunta
Vivekananda Budamagunta

H-Index: 4

Daohong Zhou
Daohong Zhou

H-Index: 37

A BCL-XL PROTAC degrader DT2216 synergizes with KRASG12C inhibitors for effectively treating KRASG12C-mutated cancers

Cancer Research

2022/6/15

Sajid Khan
Sajid Khan

H-Index: 14

Peiyi Zhang
Peiyi Zhang

H-Index: 5

Dinesh Thummuri
Dinesh Thummuri

H-Index: 18

Vivekananda Budamagunta
Vivekananda Budamagunta

H-Index: 4

Nan Hua
Nan Hua

H-Index: 13

Guangrong Zheng
Guangrong Zheng

H-Index: 15

Daohong Zhou
Daohong Zhou

H-Index: 37

BCL-XL PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRASG12C-mutated cancers

Journal of Hematology & Oncology

2022/3/9

Sajid Khan
Sajid Khan

H-Index: 14

Peiyi Zhang
Peiyi Zhang

H-Index: 5

Dinesh Thummuri
Dinesh Thummuri

H-Index: 18

Vivekananda Budamagunta
Vivekananda Budamagunta

H-Index: 4

Nan Hua
Nan Hua

H-Index: 13

Guangrong Zheng
Guangrong Zheng

H-Index: 15

Daohong Zhou
Daohong Zhou

H-Index: 37

BCL-X

2022

Sajid Khan
Sajid Khan

H-Index: 14

Peiyi Zhang
Peiyi Zhang

H-Index: 5

Dinesh Thummuri
Dinesh Thummuri

H-Index: 18

Vivekananda Budamagunta
Vivekananda Budamagunta

H-Index: 4

Nan Hua
Nan Hua

H-Index: 13

Guangrong Zheng
Guangrong Zheng

H-Index: 15

Daohong Zhou
Daohong Zhou

H-Index: 37

Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL–Specific Degrader DT2216

Molecular cancer therapeutics

2022/1/1

Dinesh Thummuri
Dinesh Thummuri

H-Index: 18

Sajid Khan
Sajid Khan

H-Index: 14

Peiyi Zhang
Peiyi Zhang

H-Index: 5

Xuan Zhang
Xuan Zhang

H-Index: 2

Vivekananda Budamagunta
Vivekananda Budamagunta

H-Index: 4

Amin Sobh
Amin Sobh

H-Index: 3

Guangrong Zheng
Guangrong Zheng

H-Index: 15

Daohong Zhou
Daohong Zhou

H-Index: 37

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity

Nature communications

2021/11/25

Dongwen Lv
Dongwen Lv

H-Index: 22

Pratik Pal
Pratik Pal

H-Index: 3

Xingui Liu
Xingui Liu

H-Index: 8

Dinesh Thummuri
Dinesh Thummuri

H-Index: 18

Peiyi Zhang
Peiyi Zhang

H-Index: 5

Qi Zhang
Qi Zhang

H-Index: 5

Shuo Zhou
Shuo Zhou

H-Index: 9

Sajid Khan
Sajid Khan

H-Index: 14

Xuan Zhang
Xuan Zhang

H-Index: 2

Nan Hua
Nan Hua

H-Index: 13

Weizhou Zhang
Weizhou Zhang

H-Index: 32

Yaxia Yuan
Yaxia Yuan

H-Index: 16

Guangrong Zheng
Guangrong Zheng

H-Index: 15

Daohong Zhou
Daohong Zhou

H-Index: 37

Discovery of a Novel BCL-XL PROTAC Degrader with Enhanced BCL-2 Inhibition

Journal of medicinal chemistry

2021/9/17

Pratik Pal
Pratik Pal

H-Index: 3

Dinesh Thummuri
Dinesh Thummuri

H-Index: 18

Dongwen Lv
Dongwen Lv

H-Index: 22

Xingui Liu
Xingui Liu

H-Index: 8

Peiyi Zhang
Peiyi Zhang

H-Index: 5

Nan Hua
Nan Hua

H-Index: 13

Sajid Khan
Sajid Khan

H-Index: 14

Yaxia Yuan
Yaxia Yuan

H-Index: 16

Xuan Zhang
Xuan Zhang

H-Index: 2

Daohong Zhou
Daohong Zhou

H-Index: 37

Guangrong Zheng
Guangrong Zheng

H-Index: 15

DEGRADER OF BCL-2 PROTEIN FOR CANCER TREATMENT

2021/6/9

BCL-2 Proteins Degraders for Cancer Treatment

2021/3/25

Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells

Nature communications

2021/2/24

Sajid Khan
Sajid Khan

H-Index: 14

Yuewan Luo
Yuewan Luo

H-Index: 4

Myung-Chul Kim
Myung-Chul Kim

H-Index: 11

Xin Zhang
Xin Zhang

H-Index: 11

Peiyi Zhang
Peiyi Zhang

H-Index: 5

Xuan Zhang
Xuan Zhang

H-Index: 2

Nicholas Borcherding
Nicholas Borcherding

H-Index: 15

Dorina Avram
Dorina Avram

H-Index: 21

Guangrong Zheng
Guangrong Zheng

H-Index: 15

Daohong Zhou
Daohong Zhou

H-Index: 37

Weizhou Zhang
Weizhou Zhang

H-Index: 32

Discovery of PROTAC BCL-XL degraders as potent anticancer agents with low on-target platelet toxicity

2020/4/15

Dinesh Thummuri
Dinesh Thummuri

H-Index: 18

Xingui Liu
Xingui Liu

H-Index: 8

Peiyi Zhang
Peiyi Zhang

H-Index: 5

Sajid Khan
Sajid Khan

H-Index: 14

Yaxia Yuan
Yaxia Yuan

H-Index: 16

Daohong Zhou
Daohong Zhou

H-Index: 37

Guangrong Zheng
Guangrong Zheng

H-Index: 15

PROTACs are effective in addressing the platelet toxicity associated with BCL-XL inhibitors

2020

Peiyi Zhang
Peiyi Zhang

H-Index: 5

Xuan Zhang
Xuan Zhang

H-Index: 2

Xingui Liu
Xingui Liu

H-Index: 8

Sajid Khan
Sajid Khan

H-Index: 14

Daohong Zhou
Daohong Zhou

H-Index: 37

Guangrong Zheng
Guangrong Zheng

H-Index: 15

Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies

2020/12

Sajid Khan
Sajid Khan

H-Index: 14

Zhiguang Huo
Zhiguang Huo

H-Index: 13

Dongwen Lv
Dongwen Lv

H-Index: 22

Xuan Zhang
Xuan Zhang

H-Index: 2

Xingui Liu
Xingui Liu

H-Index: 8

Yaxia Yuan
Yaxia Yuan

H-Index: 16

Guangrong Zheng
Guangrong Zheng

H-Index: 15

Daohong Zhou
Daohong Zhou

H-Index: 37

DT2216—a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas

Journal of hematology & oncology

2020/12

Vivekananda Budamagunta
Vivekananda Budamagunta

H-Index: 4

Peiyi Zhang
Peiyi Zhang

H-Index: 5

Xuan Zhang
Xuan Zhang

H-Index: 2

Sajid Khan
Sajid Khan

H-Index: 14

Dinesh Thummuri
Dinesh Thummuri

H-Index: 18

Xin Zhang
Xin Zhang

H-Index: 11

Dongwen Lv
Dongwen Lv

H-Index: 22

Wen Li
Wen Li

H-Index: 1

Adam C Palmer
Adam C Palmer

H-Index: 16

Guangrong Zheng
Guangrong Zheng

H-Index: 15

Daohong Zhou
Daohong Zhou

H-Index: 37

Centchroman prevents metastatic colonization of breast cancer cells and disrupts angiogenesis via inhibition of RAC1/PAK1/β-catenin signaling axis

Life Sciences

2020/9/1

Sajid Khan
Sajid Khan

H-Index: 14

PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics

2020/6/25

Sajid Khan
Sajid Khan

H-Index: 14

Xuan Zhang
Xuan Zhang

H-Index: 2

Yaxia Yuan
Yaxia Yuan

H-Index: 16

Guangrong Zheng
Guangrong Zheng

H-Index: 15

Daohong Zhou
Daohong Zhou

H-Index: 37

Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity

Nature communications

2020/4/24

Xuan Zhang
Xuan Zhang

H-Index: 2

Jianhui Chang
Jianhui Chang

H-Index: 1

Ha-Neui Kim
Ha-Neui Kim

H-Index: 19

Peiyi Zhang
Peiyi Zhang

H-Index: 5

Yingying Wang
Yingying Wang

H-Index: 5

Sajid Khan
Sajid Khan

H-Index: 14

Xingui Liu
Xingui Liu

H-Index: 8

Xin Zhang
Xin Zhang

H-Index: 11

Dongwen Lv
Dongwen Lv

H-Index: 22

Lin Song
Lin Song

H-Index: 1

Wen Li
Wen Li

H-Index: 1

Dinesh Thummuri
Dinesh Thummuri

H-Index: 18

Yaxia Yuan
Yaxia Yuan

H-Index: 16

Vivekananda Budamagunta
Vivekananda Budamagunta

H-Index: 4

Maria Almeida
Maria Almeida

H-Index: 36

Guangrong Zheng
Guangrong Zheng

H-Index: 15

Daohong Zhou
Daohong Zhou

H-Index: 37

See List of Professors in Sajid Khan University(University of Florida)

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