Robert J. Shmookler Reis
University of Arkansas for Medical Sciences
H-index: 44
North America-United States
Top articles of Robert J. Shmookler Reis
Model biological systems demonstrate the inducibility of pathways that strongly reduce cryoprotectant toxicity
Cryobiology
2024/3/2
Alzheimer’s-specific brain amyloid interactome: Neural-network analysis of intra-aggregate crosslinking identifies novel drug targets
Iscience
2024/1/19
Rescue of ApoE4-related lysosomal autophagic failure in Alzheimer’s disease by targeted small molecules
Communications Biology
2024/1/8
Leave-one-out-analysis (LOOA): web-based tool to predict influential proteins and interactions in aggregate-crosslinking proteomic data
Bioinformation
2024
Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain
Molecular and Cellular Biochemistry
2023/11/3
Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan
Pharmaceuticals
2023/10/20
Novel tdzd analogs as agents that delay, prevent, or reverse age-associated diseases and as anti-cancer and antileukemic agents
2023/4/27
In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration
Scientific Reports
2023/2/6
Protein homeostasis in the aged and diseased heart
The journal of cardiovascular aging
2023
Machine-learning analysis of intrinsically disordered proteins identifies key factors that contribute to neurodegeneration-related aggregation
Frontiers in Aging Neuroscience
2022/8/3
Glial fibrillary acidic protein: a biomarker and drug target for alzheimer’s disease
Pharmaceutics
2022/6/26
Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration
2022/1
Label-free photothermal disruption of cytotoxic aggregates rescues pathology in a C. elegans model of Huntington’s disease
Scientific Reports
2021/10/5
Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer’s disease
Bioorganic & medicinal chemistry
2021/9/1
“Protein aggregates” contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation
Aging Cell
2021/5
Design and synthesis of novel hybrid 8-hydroxy quinoline-indole derivatives as inhibitors of Aβ self-aggregation and metal chelation-induced Aβ aggregation
Molecules
2020/8/8
Computational target-based drug repurposing of elbasvir, an antiviral drug predicted to bind multiple SARS-CoV-2 proteins
ChemRxiv
2020/4/8
Structural modeling of GSK3β implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs
Scientific reports
2020/10/27
Genomic instability in multiple myeloma
2020/10/1
