Rajesh Bhardwaj

Rajesh Bhardwaj

Universität Bern

H-index: 15

Europe-Switzerland

About Rajesh Bhardwaj

Rajesh Bhardwaj, With an exceptional h-index of 15 and a recent h-index of 15 (since 2020), a distinguished researcher at Universität Bern, specializes in the field of Calcium Signaling, Ion Channels, Transporters, Structure-Function Relation, Drug Discovery.

His recent articles reflect a diverse array of research interests and contributions to the field:

ELM—the Eukaryotic Linear Motif resource—2024 update

Development of chemical tools based on GSK-7975A to study store-operated calcium entry in cells

GATING AND MOLECULAR PHARMACOLOGY OF TRP CHANNELS

Store-Operated Calcium Entry in Breast Cancer Cells Is Insensitive to Orai1 and STIM1 N-Linked Glycosylation

Discovery of novel gating checkpoints in the Orai1 calcium channel by systematic analysis of constitutively active mutants of its paralogs and orthologs

The allelic variant A391T of metal ion transporter ZIP8 (SLC39A8) leads to hypotension and enhanced insulin resistance

Dissecting gating mechanisms of Orai calcium channel paralogs using constitutively active Orai mutants that mimic STIM1-gated state

Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1

Rajesh Bhardwaj Information

University

Position

___

Citations(all)

515

Citations(since 2020)

452

Cited By

169

hIndex(all)

15

hIndex(since 2020)

15

i10Index(all)

16

i10Index(since 2020)

16

Email

University Profile Page

Google Scholar

Rajesh Bhardwaj Skills & Research Interests

Calcium Signaling

Ion Channels

Transporters

Structure-Function Relation

Drug Discovery

Top articles of Rajesh Bhardwaj

ELM—the Eukaryotic Linear Motif resource—2024 update

Nucleic acids research

2024/1/5

Development of chemical tools based on GSK-7975A to study store-operated calcium entry in cells

Cell calcium

2024/1/1

Rajesh Bhardwaj
Rajesh Bhardwaj

H-Index: 7

Martin Lochner
Martin Lochner

H-Index: 6

GATING AND MOLECULAR PHARMACOLOGY OF TRP CHANNELS

2023

Store-Operated Calcium Entry in Breast Cancer Cells Is Insensitive to Orai1 and STIM1 N-Linked Glycosylation

Cancers

2022/12/29

Rajesh Bhardwaj
Rajesh Bhardwaj

H-Index: 7

Discovery of novel gating checkpoints in the Orai1 calcium channel by systematic analysis of constitutively active mutants of its paralogs and orthologs

Cell calcium

2022/7/1

The allelic variant A391T of metal ion transporter ZIP8 (SLC39A8) leads to hypotension and enhanced insulin resistance

Frontiers in physiology

2022/6/15

Rajesh Bhardwaj
Rajesh Bhardwaj

H-Index: 7

Dissecting gating mechanisms of Orai calcium channel paralogs using constitutively active Orai mutants that mimic STIM1-gated state

bioRxiv

2021/10/26

Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1

Molecular oncology

2021/10

Rajesh Bhardwaj
Rajesh Bhardwaj

H-Index: 7

Inhibitors of human divalent metal transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB-17 fragment library

ChemMedChem

2021/11/5

Rajesh Bhardwaj
Rajesh Bhardwaj

H-Index: 7

Mahendra Awale
Mahendra Awale

H-Index: 19

The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca2+ entry

Proceedings of the National Academy of Sciences

2021/5/11

The sodium/proton exchanger NHA2 regulates blood pressure through a WNK4-NCC dependent pathway in the kidney

Kidney international

2021/2/1

Rajesh Bhardwaj
Rajesh Bhardwaj

H-Index: 7

Orai1 Boosts SK3 Channel Activation

Cancers

2021/1

Inactivation-mimicking block of the epithelial calcium channel TRPV6

Science advances

2020/11/27

Oxidative stress-induced STIM2 cysteine modifications suppress store-operated calcium entry

Cell reports

2020/10/20

STIM2 targets Orai1/STIM1 to the AKAP79 signaling complex and confers coupling of Ca2+ entry with NFAT1 activation

Proceedings of the National Academy of Sciences

2020/7/14

Ca2+/Calmodulin Binding to STIM1 Hydrophobic Residues Facilitates Slow Ca2+-Dependent Inactivation of the Orai1 Channel.

Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology

2020/3/17

Rajesh Bhardwaj
Rajesh Bhardwaj

H-Index: 7

Matthias Hediger
Matthias Hediger

H-Index: 45

Natural product inspired optimization of a selective TRPV6 calcium channel inhibitor

RSC medicinal chemistry

2020

Synthesis and Pharmacological Characterization of 2‑Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast …

Pharmacology Research & Perspectives

2019/10

See List of Professors in Rajesh Bhardwaj University(Universität Bern)

Co-Authors

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