Prakash Radhakrishnan

About Prakash Radhakrishnan

Prakash Radhakrishnan, With an exceptional h-index of 23 and a recent h-index of 16 (since 2020), a distinguished researcher at University of Nebraska Medical Center, specializes in the field of Mucin, Truncated O-glycans and pancreatic cancer.

His recent articles reflect a diverse array of research interests and contributions to the field:

Interrogating the Theranostic Capacity of a MUC16-Targeted Antibody for Ovarian Cancer

Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9. 6

MUC16 monoclonal antibody and uses thereof

Mucins as contrast agent targets for fluorescence-guided surgery of pancreatic cancer

The (Sialyl) Tn antigen: Contributions to immunosuppression in gastrointestinal cancers

Tianming Zhang1, Wenjun Li1, Danbei Diwu1, Lijun Chen1, Xi Chen2, 3 and Hong Wang1

169 Immunotherapeutic potential of the humanized anti-MUC16 antibody AR9. 6 against PDAC

Truncated O-Glycan-Bearing MUC16 enhances pancreatic cancer cells aggressiveness via α4β1 integrin complexes and FAK signaling

Prakash Radhakrishnan Information

University

Position

Associate Professor Eppley Institute for Research in Cancer

Citations(all)

2235

Citations(since 2020)

1476

Cited By

1229

hIndex(all)

23

hIndex(since 2020)

16

i10Index(all)

36

i10Index(since 2020)

30

Email

University Profile Page

Google Scholar

Prakash Radhakrishnan Skills & Research Interests

Mucin

Truncated O-glycans and pancreatic cancer

Top articles of Prakash Radhakrishnan

Interrogating the Theranostic Capacity of a MUC16-Targeted Antibody for Ovarian Cancer

Journal of Nuclear Medicine

2024/4/1

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9. 6

Molecular Cancer Therapeutics

2024/2/23

Benjamin Swanson
Benjamin Swanson

H-Index: 3

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

MUC16 monoclonal antibody and uses thereof

2023/10/3

Mucins as contrast agent targets for fluorescence-guided surgery of pancreatic cancer

2023/3/29

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

Michael Bouvet
Michael Bouvet

H-Index: 47

The (Sialyl) Tn antigen: Contributions to immunosuppression in gastrointestinal cancers

2023/1/6

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

Tianming Zhang1, Wenjun Li1, Danbei Diwu1, Lijun Chen1, Xi Chen2, 3 and Hong Wang1

2023

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

Hong Wang
Hong Wang

H-Index: 8

169 Immunotherapeutic potential of the humanized anti-MUC16 antibody AR9. 6 against PDAC

2022/11/1

Cory Brooks
Cory Brooks

H-Index: 11

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

Truncated O-Glycan-Bearing MUC16 enhances pancreatic cancer cells aggressiveness via α4β1 integrin complexes and FAK signaling

International journal of molecular sciences

2022/5/13

Divya Thomas Chemparathy
Divya Thomas Chemparathy

H-Index: 8

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth

Proceedings of the National Academy of Sciences

2022/5/3

Structure of a Therapeutic Antibody in Complex with MUC16 Reveals a Conformational Epitope Influenced by Antigen Glycosylation

FASEB journal: official publication of the Federation of American Societies for Experimental Biology

2022/5

David Goodlett
David Goodlett

H-Index: 50

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

Insect cell expression and purification of recombinant SARS‐COV‐2 spike proteins that demonstrate ACE2 binding

Protein Science

2022/5

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

ImmunoPET of ovarian and pancreatic cancer with AR9. 6, a novel MUC16-targeted therapeutic antibody

Clinical Cancer Research

2022/3/1

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

Targeting Oxidative Stress Specific NRF2 In Pancreatic Cancer Stem Cells

2022/2/19

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

Effect of MUC16 Blockade using the Humanized AR9. 6 Antibody in Patient Derived Organoid Models of PDAC

2022

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

IgE-based therapeutic combination enhances antitumor response in preclinical models of pancreatic cancer

Molecular cancer therapeutics

2021/12/1

Ying Huang
Ying Huang

H-Index: 10

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy

European journal of medicinal chemistry

2021/10/15

Mutant K-Ras Mediated Oxidative Stress in Pancreatic Cancer

2021/9/1

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

MUC4 enhances gemcitabine resistance and malignant behaviour in pancreatic cancer cells expressing cancer-associated short O-glycans

Cancer letters

2021/4/10

Hans H Wandall
Hans H Wandall

H-Index: 34

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

Isoforms of MUC16 activate oncogenic signaling through EGF receptors to enhance the progression of pancreatic cancer

Molecular Therapy

2021/4/7

Inhibition of the receptor for advanced glycation End products enhances the cytotoxic effect of gemcitabine in murine pancreatic tumors

Biomolecules

2021/4/1

Swetha Thiyagarajan
Swetha Thiyagarajan

H-Index: 1

Prakash Radhakrishnan
Prakash Radhakrishnan

H-Index: 16

See List of Professors in Prakash Radhakrishnan University(University of Nebraska Medical Center)