Pierre Chelle

Pierre Chelle

University of Waterloo

H-index: 11

North America-Canada

About Pierre Chelle

Pierre Chelle, With an exceptional h-index of 11 and a recent h-index of 11 (since 2020), a distinguished researcher at University of Waterloo, specializes in the field of Pharmacokinetics, Hemophilia, WAPPS-Hemo.

His recent articles reflect a diverse array of research interests and contributions to the field:

Canadian clinical experience on switching from standard half‐life recombinant factor VIII (rFVIII), octocog alfa, to extended half‐life rFVIII, damoctocog alfa pegol, in …

OC 24.1 Effect of the Type of F9 Mutation on the Pharmacokinetic Profile of Patients with Hemophilia B Treated with Extended Half-Life FIX Concentrates

OC 24.2 Estimated Factor VIII Activity Levels at the Time of Bleeding Events in Individuals with Hemophilia a Without Inhibitors

A personalized limited sampling approach to better estimate terminal half‐life of FVIII concentrates

Revised terminal half‐life of nonacog alfa as derived from extended sampling data: A real‐world study involving 64 haemophilia B patients on nonacog alfa regular prophylaxis

Predicting individual changes in terminal half-life after switching to extended half-life concentrates in patients with severe Hemophilia

External qualification of the Web‐Accessible Population Pharmacokinetic Service–Hemophilia (WAPPS‐Hemo) models for octocog alfa using real patient data

Terminal half‐life of FVIII and FIX according to age, blood group and concentrate type: Data from the WAPPS database

Pierre Chelle Information

University

Position

Post doctoral fellow School of Pharmacy

Citations(all)

363

Citations(since 2020)

355

Cited By

111

hIndex(all)

11

hIndex(since 2020)

11

i10Index(all)

14

i10Index(since 2020)

14

Email

University Profile Page

Google Scholar

Pierre Chelle Skills & Research Interests

Pharmacokinetics

Hemophilia

WAPPS-Hemo

Top articles of Pierre Chelle

Canadian clinical experience on switching from standard half‐life recombinant factor VIII (rFVIII), octocog alfa, to extended half‐life rFVIII, damoctocog alfa pegol, in …

Haemophilia

2024/2/20

OC 24.1 Effect of the Type of F9 Mutation on the Pharmacokinetic Profile of Patients with Hemophilia B Treated with Extended Half-Life FIX Concentrates

Research and Practice in Thrombosis and Haemostasis

2023/10/1

OC 24.2 Estimated Factor VIII Activity Levels at the Time of Bleeding Events in Individuals with Hemophilia a Without Inhibitors

2023/10/1

A personalized limited sampling approach to better estimate terminal half‐life of FVIII concentrates

Journal of Thrombosis and Haemostasis

2022/9/1

Pierre Chelle
Pierre Chelle

H-Index: 7

Alfonso Iorio
Alfonso Iorio

H-Index: 47

Revised terminal half‐life of nonacog alfa as derived from extended sampling data: A real‐world study involving 64 haemophilia B patients on nonacog alfa regular prophylaxis

Haemophilia

2022/7

Pierre Chelle
Pierre Chelle

H-Index: 7

Predicting individual changes in terminal half-life after switching to extended half-life concentrates in patients with severe Hemophilia

HemaSphere

2022/4/1

External qualification of the Web‐Accessible Population Pharmacokinetic Service–Hemophilia (WAPPS‐Hemo) models for octocog alfa using real patient data

Research and Practice in Thrombosis and Haemostasis

2021/10/1

Terminal half‐life of FVIII and FIX according to age, blood group and concentrate type: Data from the WAPPS database

Journal of Thrombosis and Haemostasis

2021/8/1

Use of population PK/PD approach to model the thrombin generation assay: assessment in haemophilia A plasma samples spiked by a TFPI antibody

Journal of Pharmacokinetics and Pharmacodynamics

2021/8

Pierre Chelle
Pierre Chelle

H-Index: 7

Comparison of single subject and population‐based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A

Haemophilia

2021/7

Pediatric dose selection for therapeutic proteins

2021/6

Pierre Chelle
Pierre Chelle

H-Index: 7

Patient-specific modelling of blood coagulation

Bulletin of Mathematical Biology

2021/5

Limited sampling strategies for accurate determination of extended half‐life factor VIII pharmacokinetics in severe haemophilia A patients

Haemophilia

2021/5

Pierre Chelle
Pierre Chelle

H-Index: 7

Pharmacokinetic implications of dosing emicizumab based on vial size: A simulation study

Haemophilia

2021/5

A novel, enriched population pharmacokinetic model for recombinant factor VIII-Fc fusion protein concentrate in hemophilia A patients

Thrombosis and haemostasis

2020/5

Development and evaluation of the population pharmacokinetic models for FVIII and FIX concentrates of the WAPPS‐Hemo project

2020/5

Pierre Chelle
Pierre Chelle

H-Index: 7

Alfonso Iorio
Alfonso Iorio

H-Index: 47

Multicentre pharmacokinetic evaluation of rFVIII‐Fc (efmoroctocog alfa) in a real life and comparison with non‐extended half‐life FVIII concentrates

Haemophilia

2020/3

Alfonso Iorio
Alfonso Iorio

H-Index: 47

Pierre Chelle
Pierre Chelle

H-Index: 7

Clustering of thrombin generation test data using a reduced mathematical model of blood coagulation

Acta Biotheoretica

2020/3

Body mass index best predicts recovery of recombinant factor VIII in underweight to obese patients with severe haemophilia A

Thrombosis and Haemostasis

2020/2

Development and Validation of a Population-Pharmacokinetic Model for Rurioctacog Alfa Pegol (Adynovate®): A Report on Behalf of the WAPPS-Hemo …

medRxiv

2023

See List of Professors in Pierre Chelle University(University of Waterloo)