Lawrence Harris

About Lawrence Harris

Lawrence Harris, With an exceptional h-index of 12 and a recent h-index of 11 (since 2020), a distinguished researcher at Victoria University of Wellington, specializes in the field of Organic Chemistry, Medicinal Chemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

Integrative Molecular Structure Elucidation and Construction of an Extended Metabolic Pathway Associated with an Ancient Innate Immune Response in COVID-19 Patients

Chemoenzymatic Synthesis of 3′-Deoxy-3′, 4′-didehydro-cytidine triphosphate (ddhCTP)

Galidesivir triphosphate promotes stalling of dengue-2 virus polymerase immediately prior to incorporation

SARS-CoV-2 infection biomarkers reveal an extended RSAD2 dependant metabolic pathway

Synthesis of a putative ddhCTP metabolite ddhC-homocysteine

An Isomer of Galidesivir That Potently Inhibits Influenza Viruses and Members of the Bunyavirales Order

The discovery of 12β-methyl-17-epi-18-nor-bile acids as potent and selective TGR5 agonists

Expedient synthesis of imino-C-nucleoside fleximers featuring a one-pot procedure to prepare aryl triazoles

Lawrence Harris Information

University

Position

Senior Scientist Ferrier Institute

Citations(all)

454

Citations(since 2020)

321

Cited By

217

hIndex(all)

12

hIndex(since 2020)

11

i10Index(all)

13

i10Index(since 2020)

13

Email

University Profile Page

Google Scholar

Lawrence Harris Skills & Research Interests

Organic Chemistry

Medicinal Chemistry

Top articles of Lawrence Harris

Integrative Molecular Structure Elucidation and Construction of an Extended Metabolic Pathway Associated with an Ancient Innate Immune Response in COVID-19 Patients

Journal of proteome research

2024/2/4

Chemoenzymatic Synthesis of 3′-Deoxy-3′, 4′-didehydro-cytidine triphosphate (ddhCTP)

ACS bio & med Chem Au

2023/7/25

Galidesivir triphosphate promotes stalling of dengue-2 virus polymerase immediately prior to incorporation

ACS Infectious Diseases

2023/7/24

Synthesis of a putative ddhCTP metabolite ddhC-homocysteine

Tetrahedron Letters

2023/4/12

An Isomer of Galidesivir That Potently Inhibits Influenza Viruses and Members of the Bunyavirales Order

ACS Medicinal Chemistry Letters

2023/3/30

The discovery of 12β-methyl-17-epi-18-nor-bile acids as potent and selective TGR5 agonists

European Journal of Medicinal Chemistry

2023/3/15

Expedient synthesis of imino-C-nucleoside fleximers featuring a one-pot procedure to prepare aryl triazoles

Organic & Biomolecular Chemistry

2023

3α,7-Dihydroxy-14(13→12)abeo-5β,12α(H),13β(H)-cholan-24-oic Acids Display Neuroprotective Properties in Common Forms of Parkinson’s Disease

Biomolecules

2022/12/30

Inhibition of the DENV2 and ZIKV RNA polymerases by Galidesivir triphosphate measured using a continuous fluorescence assay

bioRxiv

2022/12/22

Compounds and methods for treatment of bacterial infections

2022/7/28

Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication

Molecular cell

2022/5/5

Synthesis of novel C/D ring modified bile acids

Molecules

2022/4/6

Uncoupling molecular testing for SARS-CoV-2 from international supply chains

2022/1/24

The Discovery of 12β-Methyl-18-nor-Bile Acids as Potent and Selective TGR5 Agonists

2022/1/1

Synthesis of 12β-methyl-18-nor-avicholic acid analogues as potential TGR5 agonists

Organic & Biomolecular Chemistry

2022

Discovery of AL-GDa62 as a potential synthetic lethal lead for the treatment of gastric cancer

Journal of Medicinal Chemistry

2021/12/8

Mechanism-Based Inactivation of Mycobacterium tuberculosis Isocitrate Lyase 1 by (2R,3S)-2-Hydroxy-3-(nitromethyl)succinic acid

Journal of the American Chemical Society

2021/10/19

Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective

Elife

2021/10/7

Synthesis of 12β-Methyl-18-nor-bile Acids

ACS omega

2021/9/14

See List of Professors in Lawrence Harris University(Victoria University of Wellington)