Lan K Nguyen

Lan K Nguyen

Monash University

H-index: 31

Oceania-Australia

About Lan K Nguyen

Lan K Nguyen, With an exceptional h-index of 31 and a recent h-index of 21 (since 2020), a distinguished researcher at Monash University, specializes in the field of systems biology, predictive modelling, network modelling and analysis, cancer research, signalling network.

His recent articles reflect a diverse array of research interests and contributions to the field:

HPK1 inhibits CD8+ T cell effector gene expression following T cell activation

Integrative modeling and analysis of signaling crosstalk reveal molecular switches coordinating Yes-associated protein transcriptional activities

Integrative modeling uncovers p21-driven drug resistance and prioritizes therapies for PIK3CA-mutant breast cancer

GeneSurv: Multi-Gene Cancer Survival Analysis Tool

Stress pathway outputs are encoded by pH-dependent phase separation of its components.

Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically" actionable" signalling axis in triple negative breast cancer

Reduction of a biochemical network mathematical model by means of approximating activators and inhibitors as perfect inverse relationships

Multi-Dimensional Analysis of Biochemical Network Dynamics Using pyDYVIPAC

Lan K Nguyen Information

University

Position

Head of Integrated Network Modelling Laboratory

Citations(all)

3059

Citations(since 2020)

1713

Cited By

2205

hIndex(all)

31

hIndex(since 2020)

21

i10Index(all)

60

i10Index(since 2020)

46

Email

University Profile Page

Google Scholar

Lan K Nguyen Skills & Research Interests

systems biology

predictive modelling

network modelling and analysis

cancer research

signalling network

Top articles of Lan K Nguyen

HPK1 inhibits CD8+ T cell effector gene expression following T cell activation

Cancer Research

2024/3/22

Integrative modeling and analysis of signaling crosstalk reveal molecular switches coordinating Yes-associated protein transcriptional activities

Iscience

2024/3/15

Integrative modeling uncovers p21-driven drug resistance and prioritizes therapies for PIK3CA-mutant breast cancer

NPJ Precision Oncology

2024/1/26

Lan K Nguyen
Lan K Nguyen

H-Index: 20

Antonella Papa
Antonella Papa

H-Index: 15

GeneSurv: Multi-Gene Cancer Survival Analysis Tool

bioRxiv

2024

Sungyoung Shin
Sungyoung Shin

H-Index: 13

Lan K Nguyen
Lan K Nguyen

H-Index: 20

Stress pathway outputs are encoded by pH-dependent phase separation of its components.

bioRxiv

2024

Milad Ghomlaghi
Milad Ghomlaghi

H-Index: 1

Lan K Nguyen
Lan K Nguyen

H-Index: 20

Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically" actionable" signalling axis in triple negative breast cancer

bioRxiv

2024

Reduction of a biochemical network mathematical model by means of approximating activators and inhibitors as perfect inverse relationships

arXiv preprint arXiv:2309.16088

2023/9/28

Multi-Dimensional Analysis of Biochemical Network Dynamics Using pyDYVIPAC

2023/4/20

Lan K Nguyen
Lan K Nguyen

H-Index: 20

Meta-Dynamic Network Modelling for Biochemical Networks

2023/4/20

Lan K Nguyen
Lan K Nguyen

H-Index: 20

SynDISCO: A Mechanistic Modeling-Based Framework for Predictive Prioritization of Synergistic Drug Combinations Targeting Cell Signalling Networks

2023/4/20

Lan K Nguyen
Lan K Nguyen

H-Index: 20

Computational Modeling of Signaling Networks

2012

The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer

Oncogene

2023/3/10

Systematic Analysis of Network-driven Adaptive Resistance to CDK4/6 and Estrogen Receptor Inhibition using Meta-Dynamic Network Modelling

bioRxiv

2023/1/25

Lan K Nguyen
Lan K Nguyen

H-Index: 20

A Boolean-based machine learning framework identifies predictive biomarkers of HSP90-targeted therapy response in prostate cancer

Frontiers in Molecular Biosciences

2023/1/19

Lisa M Butler
Lisa M Butler

H-Index: 19

Lan K Nguyen
Lan K Nguyen

H-Index: 20

Integrative modelling of signalling network dynamics identifies cell type-selective therapeutic strategies for FGFR4-driven cancers

bioRxiv

2023/1/1

Milad Ghomlaghi
Milad Ghomlaghi

H-Index: 1

Lan K Nguyen
Lan K Nguyen

H-Index: 20

Systems modelling of TGF-β/Hippo signalling crosstalk uncovers molecular switches that coordinate YAP transcriptional complexes (submitted to iScience)

bioRxiv

2022/4/8

Milad Ghomlaghi
Milad Ghomlaghi

H-Index: 1

Lan K Nguyen
Lan K Nguyen

H-Index: 20

Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function

Immunity

2022/1/11

Feedback, crosstalk and competition: ingredients for emergent non-linear behaviour in the PI3K/mTOR signalling network

2021/6/28

Relationship Between Dimensionality and Convergence of Optimization Algorithms: A Comparison Between Data-Driven Normalization and Scaling Factor-Based Methods Using PEPSSBI

2021/12/10

See List of Professors in Lan K Nguyen University(Monash University)