Joshua Dempster

Joshua Dempster

Harvard University

H-index: 19

North America-United States

Contact Joshua Dempster

About Joshua Dempster

Joshua Dempster, With an exceptional h-index of 19 and a recent h-index of 19 (since 2020), a distinguished researcher at Harvard University, specializes in the field of data science, bioinformatics, cancer biology, machine learning.

His recent articles reflect a diverse array of research interests and contributions to the field:

Abstract LB203: CRISPR anchor screens to identify co-vulnerabilities and drug combinations in DepMap

PELO is a synthetic lethal target in chromosome 9p21-deleted or MSI cancers

Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal

DIPG-19. BAF COMPLEX PERTURBATION AS A NOVEL THERAPEUTIC OPPORTUNITY IN H3K27M PEDIATRIC GLIOMA

Defining the landscape of cancer vulnerabilities that are engendered by germline genetic variation

Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias

Abstract LB074: Towards the next generation cancer dependency map

Mapping the landscape of genetic dependencies in chordoma

Joshua Dempster Information

University	Harvard University
Position	Data Scientist, Broad Institute
Citations(all)	2504
Citations(since 2020)	2405
Cited By	804
hIndex(all)	19
hIndex(since 2020)	19
i10Index(all)	25
i10Index(since 2020)	23
Email	Access Email
University Profile Page	Harvard University
Google Scholar	View Google Scholar Profile

Joshua Dempster Skills & Research Interests

data science

bioinformatics

cancer biology

machine learning

Top articles of Joshua Dempster

Abstract LB203: CRISPR anchor screens to identify co-vulnerabilities and drug combinations in DepMap

Cancer Research

2024/4/5

Yuqi Chen

H-Index: 4

Negin Karisani

H-Index: 1

Barbara De Kegel

H-Index: 1

Francisca Vazquez

H-Index: 38

PELO is a synthetic lethal target in chromosome 9p21-deleted or MSI cancers

Cancer Research

2024/3/22

Patricia Borck

H-Index: 13

Anthony Lau

H-Index: 4

Joshua Dempster

H-Index: 10

Francisca Vazquez

H-Index: 38

Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal

Genome Biology

2023/8/23

Brenton R Paolella

H-Index: 11

James M Mcfarland

H-Index: 16

Francisca Vazquez

H-Index: 38

Aviad Tsherniak

H-Index: 36

DIPG-19. BAF COMPLEX PERTURBATION AS A NOVEL THERAPEUTIC OPPORTUNITY IN H3K27M PEDIATRIC GLIOMA

Neuro-Oncology

2023/6/1

Eshini Panditharatna

H-Index: 7

Tingjian Wang

H-Index: 9

Maria Trissal

H-Index: 9

Li Jiang

H-Index: 4

Andrew Groves

H-Index: 0

Samantha Hoffman

H-Index: 1

Joshua Dempster

H-Index: 10

Caleb Lareau

H-Index: 26

Francisca Vazquez

H-Index: 38

David Root

H-Index: 12

Jamie Anastas

H-Index: 10

Sylwia Stopka

H-Index: 10

Michael Regan

H-Index: 8

Yu Liang

H-Index: 1

Nathan Mathewson

H-Index: 16

Yang Shi

H-Index: 8

Jun Qi

H-Index: 9

Defining the landscape of cancer vulnerabilities that are engendered by germline genetic variation

2023/6/1

Sean Misek

H-Index: 6

Jeremie Kalfon

H-Index: 3

Joshua Dempster

H-Index: 10

Thomas Green

H-Index: 5

Adam Brown

H-Index: 5

David Root

H-Index: 12

James Mcfarland

H-Index: 4

Rameen Beroukhim

H-Index: 115

Jesse Boehm

H-Index: 44

Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias

Nature Cancer

2023/5

Ricardo De Matos Simoes

H-Index: 14

Michal Sheffer

H-Index: 14

James M Mcfarland

H-Index: 16

Francisca Vazquez

H-Index: 38

Aviad Tsherniak

H-Index: 36

Abstract LB074: Towards the next generation cancer dependency map

Cancer Research

2023/4/14

Kelly Sullivan

H-Index: 2

Francisca Vazquez

H-Index: 38

Mapping the landscape of genetic dependencies in chordoma

Nature Communications

2023/4/6

Sandrine Muller

H-Index: 4

Francisca Vazquez

H-Index: 38

Charting new cancer dependencies with patient derived organoids

Cancer Research

2023/4/4

Megan Wong

H-Index: 2

Barbara De Kegel

H-Index: 1

Joshua Dempster

H-Index: 10

David Root

H-Index: 12

Francisca Vazquez

H-Index: 38

A ubiquitination cascade regulating the integrated stress response and survival in carcinomas

Cancer discovery

2023/3/1

Tsukasa Shibue

H-Index: 15

Alfredo Gonzalez

H-Index: 0

John Michael Krill-Burger

H-Index: 13

James M Mcfarland

H-Index: 16

Francisca Vazquez

H-Index: 38

Phosphate dysregulation via the XPR1–KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer

Nature cancer

2022/6

Brenton R Paolella

H-Index: 11

Alfredo Gonzalez

H-Index: 0

Kentaro Ito

H-Index: 4

Jesse Boehm

H-Index: 44

James M Mcfarland

H-Index: 16

Francisca Vazquez

H-Index: 38

Comparative optimization of combinatorial CRISPR screens

Nature Communications

2022/5/5

Ruitong Li

H-Index: 1

Michael J Young

H-Index: 30

Diego J Rodriguez

H-Index: 1

Mahdi Zamanighomi

H-Index: 8

Takahiro Ito

H-Index: 11

A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia

Genes & development

2022/3/1

Yaser Heshmati

H-Index: 6

Qian Zhu

H-Index: 12

Tianxin Liu

H-Index: 3

Yan Kai

H-Index: 9

Maxim Pimkin

H-Index: 11

BAF complex maintains glioma stem cells in pediatric H3K27M glioma

Cancer discovery

2022/12/2

Eshini Panditharatna

H-Index: 7

Tingjian Wang

H-Index: 9

Li Jiang

H-Index: 4

Andrew Groves

H-Index: 0

Mckenzie L Shaw

H-Index: 7

Caleb Lareau

H-Index: 26

Francisca Vazquez

H-Index: 38

Sylwia Stopka

H-Index: 10

Yu Liang

H-Index: 1

Yang Shi

H-Index: 8

Jun Qi

H-Index: 9

Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries

bioRxiv

2022/11/19

Jeremie Kalfon

H-Index: 3

Joshua Dempster

H-Index: 10

Thomas Green

H-Index: 5

Adam Brown

H-Index: 5

David Root

H-Index: 12

James Mcfarland

H-Index: 4

Rameen Beroukhim

H-Index: 115

Transcriptional plasticity drives leukemia immune escape

Blood Cancer Discovery

2022/9/6

Yaser Heshmati

H-Index: 6

Maxim Pimkin

H-Index: 11

Phosphate dysregulation as a novel therapeutic strategy in ovarian and uterine cancers

Cancer Research

2022/6/15

Daniel Bondeson

H-Index: 7

Michael Rothberg

H-Index: 24

Alfredo Gonzalez

H-Index: 0

Kentaro Ito

H-Index: 4

Joshua Dempster

H-Index: 10

David Root

H-Index: 12

Jesse Boehm

H-Index: 44

James Mcfarland

H-Index: 4

Francisca Vazquez

H-Index: 38

Todd Golub

H-Index: 116

Ancestry bias in CRISPR guide design impedes discovery of genetic dependencies

Cancer Research

2022/6/15

Jeremie Kalfon

H-Index: 3

Joshua Dempster

H-Index: 10

James Mcfarland

H-Index: 4

Rameen Beroukhim

H-Index: 115

Jesse Boehm

H-Index: 44

Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects

Genome biology

2021/12

Francisca Vazquez

H-Index: 38

Aviad Tsherniak

H-Index: 36

James M Mcfarland

H-Index: 16

Selective modulation of a pan-essential protein as a therapeutic strategy in cancer

Cancer discovery

2021/9/1

Alfredo Gonzalez

H-Index: 0

Miljan Kuljanin

H-Index: 11

Brenton R Paolella

H-Index: 11

Volker Hovestadt

H-Index: 50

Francisca Vazquez

H-Index: 38

See List of Professors in Joshua Dempster University(Harvard University)

Co-Authors

H-index: 186

Todd Golub — Todd Golub
Harvard University

Visit Todd Golub Page

H-index: 69

Monica Olvera de la Cruz — Monica Olvera de la Cruz
North Western University

Visit Monica Olvera de la Cruz Page

H-index: 67

John G. Doench — John G. Doench
Harvard University

Visit John G. Doench Page

H-index: 55

Jesse Boehm — Jesse Boehm
Harvard University

Visit Jesse Boehm Page

H-index: 52

Francisca Vazquez — Francisca Vazquez
Harvard University

Visit Francisca Vazquez Page

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