Guo-Cheng Yuan

About Guo-Cheng Yuan

Guo-Cheng Yuan, With an exceptional h-index of 72 and a recent h-index of 64 (since 2020), a distinguished researcher at Icahn School of Medicine at Mount Sinai, specializes in the field of computational biology, gene regulation, epigenomics, single cell genomics, spatial transcriptomics.

His recent articles reflect a diverse array of research interests and contributions to the field:

Matrin3 mediates differentiation through stabilizing chromatin loop-domain interactions and YY1 mediated enhancer-promoter interactions

RECCIPE: A new framework assessing localized cell-cell interaction on gene expression in multicellular ST data

Orthogonal multimodality integration and clustering in single-cell data

Targeting of the CD161 inhibitory receptor enhances T-cell–mediated immunity against hematological malignancies

Giotto Suite: a multi-scale and technology-agnostic spatial multi-omics analysis ecosystem

Spatial transcriptomics defines injury-specific microenvironments in the adult mouse kidney and novel cellular interactions in regeneration and disease

Identifying quantitatively differential chromosomal compartmentalization changes and their biological significance from Hi-C data using DARIC

Multi-omic profiling of the developing human cerebral cortex at the single-cell level

Guo-Cheng Yuan Information

University

Position

Professor of Computational Biology

Citations(all)

24568

Citations(since 2020)

15771

Cited By

14624

hIndex(all)

72

hIndex(since 2020)

64

i10Index(all)

138

i10Index(since 2020)

119

Email

University Profile Page

Google Scholar

Guo-Cheng Yuan Skills & Research Interests

computational biology

gene regulation

epigenomics

single cell genomics

spatial transcriptomics

Top articles of Guo-Cheng Yuan

Matrin3 mediates differentiation through stabilizing chromatin loop-domain interactions and YY1 mediated enhancer-promoter interactions

Nature Communications

2024/2/10

RECCIPE: A new framework assessing localized cell-cell interaction on gene expression in multicellular ST data

Frontiers in Genetics

2024/1/24

Orthogonal multimodality integration and clustering in single-cell data

BMC bioinformatics

2024

Targeting of the CD161 inhibitory receptor enhances T-cell–mediated immunity against hematological malignancies

Blood

2024/3/21

Giotto Suite: a multi-scale and technology-agnostic spatial multi-omics analysis ecosystem

bioRxiv

2023/11/27

Spatial transcriptomics defines injury-specific microenvironments in the adult mouse kidney and novel cellular interactions in regeneration and disease

bioRxiv

2023/11/22

Identifying quantitatively differential chromosomal compartmentalization changes and their biological significance from Hi-C data using DARIC

BMC genomics

2023/10/13

Yan Kai
Yan Kai

H-Index: 9

Nan Liu
Nan Liu

H-Index: 14

Guo-Cheng Yuan
Guo-Cheng Yuan

H-Index: 51

Multi-omic profiling of the developing human cerebral cortex at the single-cell level

Science Advances

2023/10/12

Myeloid cell influx into the colonic epithelium is associated with disease severity and non-response to anti-Tumor Necrosis Factor Therapy in patients with Ulcerative Colitis

bioRxiv

2023/6/5

Distinct niche structures and intrinsic programs of fallopian tube and ovarian surface epithelial cells

Iscience

2023/1/20

QuadST: A Powerful and Robust Approach for Identifying Cell-Cell Interaction-Changed Genes on Spatially Resolved Transcriptomics

bioRxiv

2023

Broad H3K4me3 Domain Is Associated with Spatial Coherence during Mammalian Embryonic Development

bioRxiv

2023

Xuan Cao
Xuan Cao

H-Index: 11

Rong Fan
Rong Fan

H-Index: 7

Guo-Cheng Yuan
Guo-Cheng Yuan

H-Index: 51

Plasticity of Human Microglia and Brain Perivascular Macrophages in Aging and Alzheimer's Disease

medRxiv

2023

Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer’s disease: review, recommendation, implementation and application

2022/3/2

CUT&RUNTools 2.0: a pipeline for single-cell and bulk-level CUT&RUN and CUT&Tag data analysis

Bioinformatics

2022/1/1

Guo-Cheng Yuan
Guo-Cheng Yuan

H-Index: 51

The landscape of human tissue and cell type specific expression and co-regulation of senescence genes

Molecular Neurodegeneration

2022/12

A vaccine targeting resistant tumours by dual T cell plus NK cell attack

Nature

2022/6/30

Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer

Molecular Cancer Research

2022/5/4

See List of Professors in Guo-Cheng Yuan University(Icahn School of Medicine at Mount Sinai)

Co-Authors

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