Guangrong Zheng
University of Florida
H-index: 33
North America-United States
Top articles of Guangrong Zheng
Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL
Nature communications
2024/3/29
Dongwen Lv
H-Index: 22
Yaxia Yuan
H-Index: 16
Peiyi Zhang
H-Index: 5
Guangrong Zheng
H-Index: 15
Daohong Zhou
H-Index: 37
Attenuating breast cancer metastasis with BCL-XL-targeting PROTACs
Cancer Research
2024/3/22
Rational targeting of BCL-xL and/or mTOR enhance the efficacy of KRASG12D inhibitor in pancreatic cancer
Cancer Research
2024/3/22
Sajid Khan
H-Index: 14
Lin Cao
H-Index: 11
Yang Yang
H-Index: 9
Peiyi Zhang
H-Index: 5
Guangrong Zheng
H-Index: 15
Daohong Zhou
H-Index: 37
Discovery of hydrazide-based HDAC8 selective PROTACs
Cancer Research
2024/3/22
Yufeng Xiao
H-Index: 2
Yi Liu
H-Index: 21
Robert Kridel
H-Index: 27
Daiqing Liao
H-Index: 12
Guangrong Zheng
H-Index: 15
PROTAC-mediated dual degradation of BCL-xL and BCL-2 is a highly effective therapeutic strategy in small-cell lung cancer
Cells
2024/3/17
Sajid Khan
H-Index: 14
Lin Cao
H-Index: 11
Peiyi Zhang
H-Index: 5
Guangrong Zheng
H-Index: 15
Daohong Zhou
H-Index: 37
Abstract 1209 Structural And Biochemical Studies Of Proteolysis-Targeting Chimera (PROTAC) Against Oncogenic Anti-Apoptotic Proteins, BCL-xl And Bcl-2
Journal of Biological Chemistry
2024/3/1
Guangrong Zheng
H-Index: 15
PROTAC-mediated NR4A1 degradation as a novel strategy for cancer immunotherapy
Journal of Experimental Medicine
2024/2/9
Design and optimization of piperlongumine analogs as potent senolytics
Bioorganic & Medicinal Chemistry Letters
2024/1/15
Targeting intracellular proteins with cell type-specific functions for cancer immunotherapy
2023/6/1
ROS-mediated SRMS activation confers platinum resistance in ovarian cancer
Oncogene
2023/5/12
Proteolysis-targeting chimera against NR4A1 for cancer immunotherapy
The Journal of Immunology
2023/5/1
Abstract LB002: Extracellular vesicle loading of proteolysis targeting chimeras for targeted therapeutic delivery
Cancer Research
2023/4/14
Xiaoshu Pan
H-Index: 11
Yufeng Xiao
H-Index: 2
Guangrong Zheng
H-Index: 15
Daiqing Liao
H-Index: 12
Mei He
H-Index: 13
Developing a PROTAC-based NR4A1 degrader for melanoma cancer therapy
Cancer Research
2023/4/4
Selective targeting deacetylase 3 (HDAC3) and HDAC8 by PROTACs
Cancer Research
2023/4/4
PROTAC therapy as a new targeted therapy for lung cancer
2023/3/1
Guangrong Zheng
H-Index: 15
Lizi Wu
H-Index: 26
Piperlongumine conjugates induce targeted protein degradation
Cell Chemical Biology
2023/2/16
Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy (vol 113, pg 1285, 2021)
JNCI: Journal of the National Cancer Institute
2021/10/1
Abstract B009: A liver-tropic BCL-xL PROTAC effectively clears senescent hepatocytes and prevents NASH-driven HCC in mice
Cancer Research
2023/1/15
Yang Yang
H-Index: 9
Peiyi Zhang
H-Index: 5
Guangrong Zheng
H-Index: 15
Liya Pi
H-Index: 17
Daohong Zhou
H-Index: 37
Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice
Cell Death Discovery
2023/1/2
Co-targeting BCL-XL and BCL-2 by PROTAC 753B eliminates leukemia cells and enhances efficacy of chemotherapy by targeting senescent cells
Haematologica
2023/10/10
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