Francesc Xavier Ruiz

About Francesc Xavier Ruiz

Francesc Xavier Ruiz, With an exceptional h-index of 24 and a recent h-index of 18 (since 2020), a distinguished researcher at Rutgers, The State University of New Jersey, specializes in the field of Enzymology, Aldo-keto Reductases, Enzyme Inhibition, Structural Biology, HIV-1 Reverse Transcriptase.

His recent articles reflect a diverse array of research interests and contributions to the field:

Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening

Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach

Structures, functions, and adaptations of the human LINE-1 ORF2 protein

Discovery of diarylpyrimidine derivatives bearing piperazine sulfonyl as potent HIV-1 nonnucleoside reverse transcriptase inhibitors

Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro

Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation

Structural basis of HIV inhibition by L-nucleosides: opportunities for drug development and repurposing

Francesc Xavier Ruiz Information

University

Position

Assistant Professor Center for Advanced Biotechnology & Medicine

Citations(all)

1950

Citations(since 2020)

1098

Cited By

1259

hIndex(all)

24

hIndex(since 2020)

18

i10Index(all)

33

i10Index(since 2020)

31

Email

University Profile Page

Google Scholar

Francesc Xavier Ruiz Skills & Research Interests

Enzymology

Aldo-keto Reductases

Enzyme Inhibition

Structural Biology

HIV-1 Reverse Transcriptase

Top articles of Francesc Xavier Ruiz

Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

Science

2024/3/29

Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening

Journal of Medicinal Chemistry

2023/4/28

Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach

Molecules

2023/3/30

Structures, functions, and adaptations of the human LINE-1 ORF2 protein

Nature

2023/12/14

Discovery of diarylpyrimidine derivatives bearing piperazine sulfonyl as potent HIV-1 nonnucleoside reverse transcriptase inhibitors

Communications Chemistry

2023/4/29

Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro

Science Advances

2022/12/9

Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation

Science Advances

2022/7/6

Francesc Xavier Ruiz
Francesc Xavier Ruiz

H-Index: 16

Eddy Arnold
Eddy Arnold

H-Index: 42

Structural basis of HIV inhibition by L-nucleosides: opportunities for drug development and repurposing

2022/2/23

Perspective on the Structural Basis for Human Aldo-Keto Reductase 1B10 Inhibition

2021/12

Francesc Xavier Ruiz
Francesc Xavier Ruiz

H-Index: 16

HIV-1 gp120 Antagonists Also Inhibit HIV-1 Reverse Transcriptase by Bridging the NNRTI and NRTI Sites

Journal of Medicinal Chemistry

2021/11/4

Cryo-EM Structure of the Pol Polyprotein Provides Insights into HIV Maturation

2021/10/4

Francesc Xavier Ruiz
Francesc Xavier Ruiz

H-Index: 16

Eddy Arnold
Eddy Arnold

H-Index: 42

Revealing the Structural Plasticity of SARS-CoV-2 nsp7 and nsp8 Using Structural Proteomics

Journal of the American Society for Mass Spectrometry

2021/6/14

2, 4, 5-Trisubstituted Pyrimidines as Potent HIV-1 NNRTIs: Rational Design, Synthesis, Activity Evaluation, and Crystallographic Studies

Journal of Medicinal Chemistry

2021/3/18

Correction to

International Journal of Social Robotics

2022

Resolving the dynamic motions of SARS-CoV-2 nsp7 and nsp8 proteins using structural proteomics

bioRxiv

2021/3/6

Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT)

bioRxiv

2021/1/1

Kalyan Das
Kalyan Das

H-Index: 35

Francesc Xavier Ruiz
Francesc Xavier Ruiz

H-Index: 16

Eddy Arnold
Eddy Arnold

H-Index: 42

Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG …

Journal of medicinal chemistry

2020/1/14

Integrative structural biology studies of HIV-1 reverse transcriptase binding to a high-affinity DNA aptamer

Current Research in Structural Biology

2020/1/1

Evolving understanding of HIV-1 reverse transcriptase structure, function, inhibition, and resistance

Current Opinion in Structural Biology

2020

Francesc Xavier Ruiz
Francesc Xavier Ruiz

H-Index: 16

Eddy Arnold
Eddy Arnold

H-Index: 42

See List of Professors in Francesc Xavier Ruiz University(Rutgers, The State University of New Jersey)