douglas R higgs

douglas R higgs

University of Oxford

H-index: 112

Europe-United Kingdom

About douglas R higgs

douglas R higgs, With an exceptional h-index of 112 and a recent h-index of 56 (since 2020), a distinguished researcher at University of Oxford, specializes in the field of gene expression, erythropoiesis, human genetics.

His recent articles reflect a diverse array of research interests and contributions to the field:

Beginnings: the molecular pathology of hemoglobin

Sir David John Weatherall. 9 March 1933—8 December 2018

Haemoglobin Bart's Hydrops Fetalis: Charting the Past and Envisioning the Future

Super-enhancers include classical enhancers and facilitators to fully activate gene expression

Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes

RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation

Understanding fundamental principles of enhancer biology at a model locus: Analysing the structure and function of an enhancer cluster at the α‐globin locus

Ancient genomic linkage couples metabolism with erythroid development

douglas R higgs Information

University

Position

Professor of haematology

Citations(all)

44114

Citations(since 2020)

11439

Cited By

38647

hIndex(all)

112

hIndex(since 2020)

56

i10Index(all)

348

i10Index(since 2020)

171

Email

University Profile Page

Google Scholar

douglas R higgs Skills & Research Interests

gene expression

erythropoiesis

human genetics

Top articles of douglas R higgs

Beginnings: the molecular pathology of hemoglobin

Molecular Hematology

2024/5/28

Sir David John Weatherall. 9 March 1933—8 December 2018

BIOGRAPHICAL MEMOIRS OF FELLOWS OF THE ROYAL SOCIETY

2023/11/29

Douglas R Higgs
Douglas R Higgs

H-Index: 54

Haemoglobin Bart's Hydrops Fetalis: Charting the Past and Envisioning the Future

Blood Journal

2024/3/8

Siyu Liu
Siyu Liu

H-Index: 11

Douglas R Higgs
Douglas R Higgs

H-Index: 54

Super-enhancers include classical enhancers and facilitators to fully activate gene expression

Cell

2023/12/21

Leslie Mitchell
Leslie Mitchell

H-Index: 23

Douglas R Higgs
Douglas R Higgs

H-Index: 54

Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes

bioRxiv

2023/11/21

RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation

Developmental Cell

2023/10/23

Understanding fundamental principles of enhancer biology at a model locus: Analysing the structure and function of an enhancer cluster at the α‐globin locus

2023/10

Ancient genomic linkage couples metabolism with erythroid development

bioRxiv

2023/9/25

Direct correction of haemoglobin E β-thalassaemia using base editors

Nature Communications

2023/4/19

Active regulatory elements recruit cohesin to establish cell-specific chromatin domains.

bioRxiv

2023

Loop extrusion by cohesin plays a key role in enhancer-activated gene expression during differentiation

bioRxiv

2023

The characteristics of CTCF binding sequences contribute to enhancer blocking activity

bioRxiv

2023

An Ancient Transcriptional Hub Couples Developmentally Regulated Gene Expression with Metabolism during Erythropoiesis

Blood

2022/11/15

On-microscope staging of live cells reveals changes in the dynamics of transcriptional bursting during differentiation

Nature Communications

2022/11/4

Multipartite super-enhancers function in an orientation-dependent manner

BioRxiv

2022/7/14

Andrew Smith
Andrew Smith

H-Index: 8

Douglas R Higgs
Douglas R Higgs

H-Index: 54

Functional impairment of erythropoiesis in Congenital Dyserythropoietic Anaemia type I arises at the progenitor level

British Journal of Haematology

2022/7

Super-enhancers require a combination of classical enhancers and novel facilitator elements to drive high levels of gene expression

Biorxiv

2022/6/21

The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin

Nature Communications

2022/6/17

Editing of haemoglobin genes

2022/2/3

Scalable in vitro production of defined mouse erythroblasts

Plos one

2022/1/7

Andrew J King
Andrew J King

H-Index: 6

Douglas R Higgs
Douglas R Higgs

H-Index: 54

See List of Professors in douglas R higgs University(University of Oxford)