Alexander Metz

About Alexander Metz

Alexander Metz, With an exceptional h-index of 12 and a recent h-index of 10 (since 2020), a distinguished researcher at Philipps-Universität Marburg, specializes in the field of Drug Design, FBLD, Fragment Screening, X-ray Crystallography, Structural Bioinformatics.

His recent articles reflect a diverse array of research interests and contributions to the field:

HEIDI: an experiment-management platform enabling high-throughput fragment and compound screening

Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket

Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at …

Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2

Probing ligand binding of endothiapepsin bytemperature-resolved'macromolecular crystallography

Frag4Lead: growing crystallographic fragment hits by catalog using fragment-guided template docking

Efficiently from library to hit–crystallographic fragment screening in Berlin via structurally diverse compound libraries

Targeting a Cryptic Pocket in a Protein–Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface

Alexander Metz Information

University

Position

Postdoctoral Researcher at

Citations(all)

652

Citations(since 2020)

340

Cited By

460

hIndex(all)

12

hIndex(since 2020)

10

i10Index(all)

15

i10Index(since 2020)

12

Email

University Profile Page

Google Scholar

Alexander Metz Skills & Research Interests

Drug Design

FBLD

Fragment Screening

X-ray Crystallography

Structural Bioinformatics

Top articles of Alexander Metz

HEIDI: an experiment-management platform enabling high-throughput fragment and compound screening

Acta Crystallographica Section D: Structural Biology

2024/5/1

Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket

Acta Crystallographica Section D: Structural Biology

2024/2/1

Alexander Metz
Alexander Metz

H-Index: 10

Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at …

bioRxiv

2024

Alexander Metz
Alexander Metz

H-Index: 10

Rajaram Venkatesan
Rajaram Venkatesan

H-Index: 7

Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2

Acta Crystallographica Section D: Structural Biology

2023/4/1

Alexander Metz
Alexander Metz

H-Index: 10

Probing ligand binding of endothiapepsin bytemperature-resolved'macromolecular crystallography

Acta Crystallographica Section D: Structural Biology

2022/8/1

Alexander Metz
Alexander Metz

H-Index: 10

Frag4Lead: growing crystallographic fragment hits by catalog using fragment-guided template docking

Acta Crystallographica Section D: Structural Biology

2021/9/1

Alexander Metz
Alexander Metz

H-Index: 10

Efficiently from library to hit–crystallographic fragment screening in Berlin via structurally diverse compound libraries

Acta Crystallographica Section A: Foundations and Advances

2021/8/14

Targeting a Cryptic Pocket in a Protein–Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface

ACS chemical biology

2021/6/3

Inhibitors of nhr2 and/or runx1/eto-tetramerization

2021/5/20

Workflow and tools for crystallographic fragment screening at the Helmholtz-Zentrum Berlin

JoVE (Journal of Visualized Experiments)

2021/3/3

Alexander Metz
Alexander Metz

H-Index: 10

F2X-universal and F2X-entry: structurally diverse compound libraries for crystallographic fragment screening

Structure

2020/6/2

Alexander Metz
Alexander Metz

H-Index: 10

See List of Professors in Alexander Metz University(Philipps-Universität Marburg)

Co-Authors

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