Aedin Culhane

Aedin Culhane

Harvard University

H-index: 50

North America-United States

About Aedin Culhane

Aedin Culhane, With an exceptional h-index of 50 and a recent h-index of 35 (since 2020), a distinguished researcher at Harvard University, specializes in the field of Bioinformatics, tumor immunology, Multiomics, single cell, matrix factorization.

His recent articles reflect a diverse array of research interests and contributions to the field:

Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model

demuxSNP: supervised demultiplexing scRNAseq using cell hashing and SNPs

Curated single cell multimodal landmark datasets for R/Bioconductor

Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias

fine-tuned CAIX targeted CAR-T cells exhibit superior efficacy and mitigate on-target off-tumor side effects

Correspondence analysis for dimension reduction, batch integration, and visualization of single-cell rna-seq data

The Minimal Dataset for Cancer of the 1+ Million Genomes Initiative

P-182 Natural killer cells are active against myeloma cells with loss of tumor suppressor genes

Aedin Culhane Information

University

Position

Dept of Data Science, Dana-Farber Cancer Institute/ Dept of Biostatistics, Harvard TH Chan School

Citations(all)

14799

Citations(since 2020)

8141

Cited By

9515

hIndex(all)

50

hIndex(since 2020)

35

i10Index(all)

75

i10Index(since 2020)

59

Email

University Profile Page

Google Scholar

Aedin Culhane Skills & Research Interests

Bioinformatics

tumor immunology

Multiomics

single cell

matrix factorization

Top articles of Aedin Culhane

Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model

Iscience

2024/2/16

demuxSNP: supervised demultiplexing scRNAseq using cell hashing and SNPs

bioRxiv

2024

Curated single cell multimodal landmark datasets for R/Bioconductor

PLOS Computational Biology

2023/8/25

Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias

Nature Cancer

2023/5

fine-tuned CAIX targeted CAR-T cells exhibit superior efficacy and mitigate on-target off-tumor side effects

Cancer Research

2023/4/4

Correspondence analysis for dimension reduction, batch integration, and visualization of single-cell rna-seq data

Scientific Reports

2023/1/21

The Minimal Dataset for Cancer of the 1+ Million Genomes Initiative

bioRxiv

2023

P-182 Natural killer cells are active against myeloma cells with loss of tumor suppressor genes

Clinical Lymphoma Myeloma and Leukemia

2023/9/1

Multi-omic spatial profiling reveals the unique virus-driven immune landscape of COVID-19 placentitis

bioRxiv

2022/11/14

Anti-CAIX Immune Restoring (IR) CAR-T cells display superior antitumor activity and reverse immunosuppressive TME in a humanized ccRCC orthotopic mouse model

Cancer Research

2022/6/15

Anti-CAIX BBζ CAR4/8 T cells exhibit superior efficacy in a ccRCC mouse model

Molecular Therapy-Oncolytics

2022/3/17

development of dual-targeted fine-tuned immune restoring (DFIR) CAR T cell therapy for clear cell renal cell carcinoma (ccRCC)

Cancer Research

2021/7/1

Treatment-induced embryonic diapause-like adaptation through suppression of Myc activity as mediator of drug persistence in cancer

Cancer Research

2021/7/1

Ricardo De Matos Simoes
Ricardo De Matos Simoes

H-Index: 14

Aedin Culhane
Aedin Culhane

H-Index: 32

Abstract GS1-07: Treatment persistence of residual breast tumors through an embryonic diapause-like cancer cell state with suppressed myc activity

Cancer Research

2021/2/15

Abstract PO041: Landscape of molecular events regulating tumor cell responses to natural killer cells

Cancer Immunology Research

2021/2/1

See List of Professors in Aedin Culhane University(Harvard University)

Co-Authors

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