Adam C Palmer

About Adam C Palmer

Adam C Palmer, With an exceptional h-index of 22 and a recent h-index of 21 (since 2020), a distinguished researcher at University of North Carolina at Chapel Hill, specializes in the field of Systems Pharmacology, Combination Therapy.

His recent articles reflect a diverse array of research interests and contributions to the field:

Ultrasensitive response explains the benefit of combination chemotherapy despite drug antagonism

Mechanistic models of tumor and patient heterogeneity explain and predict clinical outcomes of large B-cell lymphoma (LBCL) treatment

Synergistic drug combinations promote the development of resistance in acute myeloid leukemia

Tumor-specific activity of precision medicines in the NCI-MATCH trial

Abstract A135: Are survival benefits of new drugs in combinations due to modest benefits in most patients or large benefits in few patients?

Additivity predicts the efficacy of most approved combination therapies for advanced cancer

Genetically informed therapy for lymphoma: the discomfiting benefit of lumping splits

Cell-of-origin subtypes and therapeutic benefit from polatuzumab vedotin

Adam C Palmer Information

University

Position

Assistant Professor

Citations(all)

2830

Citations(since 2020)

1986

Cited By

1555

hIndex(all)

22

hIndex(since 2020)

21

i10Index(all)

26

i10Index(since 2020)

26

Email

University Profile Page

Google Scholar

Adam C Palmer Skills & Research Interests

Systems Pharmacology

Combination Therapy

Top articles of Adam C Palmer

Ultrasensitive response explains the benefit of combination chemotherapy despite drug antagonism

Molecular Cancer Therapeutics

2024/3/26

Amy E Pomeroy
Amy E Pomeroy

H-Index: 2

Adam C Palmer
Adam C Palmer

H-Index: 16

Mechanistic models of tumor and patient heterogeneity explain and predict clinical outcomes of large B-cell lymphoma (LBCL) treatment

Cancer Research

2024/3/22

Amy E Pomeroy
Amy E Pomeroy

H-Index: 2

Adam C Palmer
Adam C Palmer

H-Index: 16

Synergistic drug combinations promote the development of resistance in acute myeloid leukemia

Blood Cancer Discovery

2024/3/1

Amy E Pomeroy
Amy E Pomeroy

H-Index: 2

Adam C Palmer
Adam C Palmer

H-Index: 16

Tumor-specific activity of precision medicines in the NCI-MATCH trial

Clinical Cancer Research

2024/2/16

Deborah Plana
Deborah Plana

H-Index: 7

Adam C Palmer
Adam C Palmer

H-Index: 16

Abstract A135: Are survival benefits of new drugs in combinations due to modest benefits in most patients or large benefits in few patients?

Molecular Cancer Therapeutics

2023/12/1

Haeun Hwangbo
Haeun Hwangbo

H-Index: 1

Adam C Palmer
Adam C Palmer

H-Index: 16

Additivity predicts the efficacy of most approved combination therapies for advanced cancer

Nature Cancer

2023/12

Genetically informed therapy for lymphoma: the discomfiting benefit of lumping splits

Cancer Cell

2023/10/9

Adam C Palmer
Adam C Palmer

H-Index: 16

Cell-of-origin subtypes and therapeutic benefit from polatuzumab vedotin

New England Journal of Medicine

2023/8/24

Adam C Palmer
Adam C Palmer

H-Index: 16

An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types

bioRxiv

2023/4/29

Rationales for Combining Therapies to Treat Cancer: Independent Action, Response Correlation, and Collateral Sensitivity Versus Synergy

2023/4/11

Adam C Palmer
Adam C Palmer

H-Index: 16

Cong Chen
Cong Chen

H-Index: 7

Additivity predicts the clinical efficacy of most approved combination therapies for advanced cancer

Cancer Research

2023/4/4

Drug independence and the curability of cancer by combination chemotherapy

2022/11/1

Amy E Pomeroy
Amy E Pomeroy

H-Index: 2

Adam C Palmer
Adam C Palmer

H-Index: 16

Predicting in vivo activity of combination therapies from in vitro drug pairs in diverse environments

Cell Reports Medicine

2022/9/20

Defining and evaluating drug additivity in clinical trials of combination cancer therapy

Cancer Research

2022/6/15

Haeun Hwangbo
Haeun Hwangbo

H-Index: 1

Adam C Palmer
Adam C Palmer

H-Index: 16

Independent drug action in combination therapy: implications for precision oncology

2022/3/1

Deborah Plana
Deborah Plana

H-Index: 7

Adam C Palmer
Adam C Palmer

H-Index: 16

Cancer patient survival can be parametrized to improve trial precision and reveal time-dependent therapeutic effects

Nature communications

2022/2/15

Deborah Plana
Deborah Plana

H-Index: 7

Adam C Palmer
Adam C Palmer

H-Index: 16

Predictable clinical benefits without evidence of synergy in trials of combination therapies with immune-checkpoint inhibitors

Clinical Cancer Research

2022/1/15

Mechanisms of antibiotic action shape the fitness landscapes of resistance mutations

Computational and Structural Biotechnology Journal

2022/1/1

Predictable clinical benefits without synergy in trials of combination therapies with immune checkpoint inhibitors

Clin. Cancer Res.

2021/3/19

See List of Professors in Adam C Palmer University(University of North Carolina at Chapel Hill)

Co-Authors

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