Abdelkader Dahchour

Abdelkader Dahchour

Université Sidi Mohamed Ben Abdellah

H-index: 15

Africa-Morocco

Abdelkader Dahchour Information

University

Université Sidi Mohamed Ben Abdellah

Position

Fez Morocco

Citations(all)

1375

Citations(since 2020)

184

Cited By

1132

hIndex(all)

15

hIndex(since 2020)

9

i10Index(all)

16

i10Index(since 2020)

9

Email

University Profile Page

Université Sidi Mohamed Ben Abdellah

Abdelkader Dahchour Skills & Research Interests

Neuropharmacologie

Addiction Biology

Medicinal plants

Top articles of Abdelkader Dahchour

Changes in serotonin neurotransmission as assayed by microdialysis after acute, intermittent or chronic ethanol administration and withdrawal

Background The serotonergic neurotransmitter system is involved in many ethanol‐induced changes, including many behavioural alterations, as well as contributing to alcohol dependence and its withdrawal. Aims This review has evaluated microdialysis studies where alterations in the serotonin system, that is, serotonin, 5‐HT, or its metabolite 5‐hydroxyindoleacetic acid, 5‐HIAA, have been reported during different ethanol intoxication states, as well as in animals showing alcohol preference or not. Changes in 5‐HT receptors and the 5‐HT transporter are briefly reviewed to comprehend the significance of changes in microdialysate 5‐HT concentrations. Materials and methods Changes in 5‐HT content following acute, chronic and during ethanol withdrawal states are evaluated. In addition, the serotoninergic system was assessed in animals that have been genetically selected for alcohol preference to …

Authors

Abdelkader Dahchour,Roberta J Ward

Published Date

2024/2

Changes in brain dopamine extracellular concentration after ethanol administration; rat microdialysis studies

Aims The purpose of this review is to evaluate microdialysis studies where alterations in the dopaminergic system have been evaluated after different intoxication states, in animals showing preference or not for alcohol, as well as during alcohol withdrawal. Methods Ethanol administration induces varying alterations in dopamine microdialysate concentrations, thereby modulating the functional output of the dopaminergic system. Results Administration of low doses of ethanol, intraperitoneally, intravenously, orally or directly into the nucleus accumbens, NAc, increases mesolimbic dopamine, transmission, as shown by increases in dopamine content. Chronic alcohol administration to rats, which show alcohol-dependent behaviour, induced little change in basal dopamine microdialysis content. In contrast, reduced basal dopamine content occurred after …

Authors

Abdelkader Dahchour,Roberta J Ward

Published Date

2022/3

Anxiolytic and antidepressive potentials of rosmarinic acid: A review with a focus on antioxidant and anti-inflammatory effects

Depression and anxiety are the most prevalent neuropsychiatric disorders that have emerged as global health concerns. Anxiolytic and antidepressant drugs, such as benzodiazepines, selective serotonin reuptake inhibitors, monoamine oxidase inhibitors, and tricyclics, are the first line used in treating anxiety and depression. Although these drugs lack efficacy and have a delayed response time and numerous side effects, their widespread abuse and market continue to grow. Over time, traditional practices using natural and phytochemicals as alternative therapies to chemical drugs have emerged to treat many pathological conditions, including anxiety and depression. Recent preclinical studies have demonstrated that the phenolic compound, rosmarinic acid, is effective against several neuropsychiatric disorders, including anxiety and depression. In addition, rosmarinic acid showed various pharmacological effects …

Authors

Abdelkader Dahchour

Published Date

2022/10/1

The effects of saffron (Crocus sativus L.) and its components on depression: From basic to clinical studies

Depression is the most prevalent neuropsychiatric disorder that has emerged as a global health concern. Antidepressant drugs, such as selective serotonin reuptake inhibitors, monoamine oxidase inhibitors, and tricyclic are the first line used in treating depression. Although these drugs lack efficacy and have a delayed response time and numerous side effects, their widespread abuse and market continue to grow. Over time, traditional practices using natural and phytochemicals have emerged to treat many pathological conditions, including depression. These alternative therapies to chemical drugs show efficacy in depression with few or no side effects. Saffron is one of these alternatives that showed interesting pharmacological effects, such as antioxidant, anti-inflammatory, antihypertensive, anti-convulsant, antitussive, anxiolytic aphrodisiac, and antidepressant activity. This review will provide evidence of the use of saffron and its bioactive constituents in depression. Several preclinical and clinical studies have demonstrated that saffron and its phytochemical compounds, particularly crocin, crocetin, and safranal showed antidepressive proprieties. These effects are associated with the antioxidant, anti-inflammatory and neuroprotective actions of saffron or its ability to modulate the levels of neurotransmitters in the brain, particularly serotonin, dopamine, glutamate, and GABA.

Authors

Abdelkader Dahchour

Journal

Moroccan J. Biol

Published Date

2021

Postoperative cognitive recovery in children after both general and locoregional anesthesia and surgery

MethodsIn the present cross-sectional study, 64 young children, aged between 10 and 15 years, have passed the CALM test (software based on trial and error method) 24h after their surgery, and the operating file filled by the anesthetist. The statistical analysis includes a descriptive part of our sample, a univariate, and multivariate analysis of the results of the CALM test and the various medical factors and lifestyles.

Authors

Jalal El Hammoumi,Abdelkader Dahchour,Elmehdi Chhiti,Saïd Benlamkadem,Mohamed-Adnane Berdai,Mustapha Harandou,Saïd Boujraf

Published Date

2020/5/8

Abdelkader Dahchour FAQs

What is Abdelkader Dahchour's h-index at Université Sidi Mohamed Ben Abdellah?

The h-index of Abdelkader Dahchour has been 9 since 2020 and 15 in total.

What are Abdelkader Dahchour's top articles?

The articles with the titles of

Changes in serotonin neurotransmission as assayed by microdialysis after acute, intermittent or chronic ethanol administration and withdrawal

Changes in brain dopamine extracellular concentration after ethanol administration; rat microdialysis studies

Anxiolytic and antidepressive potentials of rosmarinic acid: A review with a focus on antioxidant and anti-inflammatory effects

The effects of saffron (Crocus sativus L.) and its components on depression: From basic to clinical studies

Postoperative cognitive recovery in children after both general and locoregional anesthesia and surgery

are the top articles of Abdelkader Dahchour at Université Sidi Mohamed Ben Abdellah.

What are Abdelkader Dahchour's research interests?

The research interests of Abdelkader Dahchour are: Neuropharmacologie, Addiction Biology, Medicinal plants

What is Abdelkader Dahchour's total number of citations?

Abdelkader Dahchour has 1,375 citations in total.

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