Abdelbasset Boubakri

Abdelbasset Boubakri

Universität Bern

H-index: 4

Europe-Switzerland

About Abdelbasset Boubakri

Abdelbasset Boubakri, With an exceptional h-index of 4 and a recent h-index of 4 (since 2020), a distinguished researcher at Universität Bern, specializes in the field of Organic Chemistry, Cell and Molecuar Biology, Insect control, Food Science, Agriculture Science.

Abdelbasset Boubakri Information

University

Universität Bern

Position

Institute of Plant Sciences Switzerland

Citations(all)

99

Citations(since 2020)

98

Cited By

21

hIndex(all)

4

hIndex(since 2020)

4

i10Index(all)

4

i10Index(since 2020)

4

Email

University Profile Page

Universität Bern

Abdelbasset Boubakri Skills & Research Interests

Organic Chemistry

Cell and Molecuar Biology

Insect control

Food Science

Agriculture Science

Top articles of Abdelbasset Boubakri

Biochemical Composition and Biological Activities of Various Population of Brassica tournefortii Growing Wild in Tunisia

Date palm (Phoenix dactylifera L.) is an essential agricultural crop in most Middle Eastern countries, and its fruit, known as dates, is consumed by millions of people. Date seeds, a by-product of the date fruit processing industry, are a waste product used as food for domestic farm animals. Date seeds contain abundant sources of carbohydrates, oil, dietary fiber, and protein; they also contain bioactive phenolic compounds that may possess potential biological properties. In addition, its rich chemical composition makes date seeds suitable for use in food product formulation, cosmetics, and medicinal supplements. This review aims to provide a discourse on the nutritional value of date seeds. The latest data on the cytotoxicity of date seed compounds against cancer cell lines, its ability to combat diabetes, antioxidant potential, antimicrobial effect, and anti-inflammatory activity will be provided, considering its potential to be a nutritional therapeutic agent for chronic diseases. Application of date seeds in the form of powder and oil will also be discussed.

Authors

Maryam Abdulraheem Alkhoori,Amanda Shen-Yee Kong,Mariam Nasser Aljaafari,Aisha Abushelaibi,Swee-Hua Erin Lim,Wan-Hee Cheng,Chou-Min Chong,Kok-Song Lai

Published Date

2022/11/3

Effect of freeze‐drying on the antioxidant and the cytotoxic properties of Allium roseum L. and its application in stabilizing food emulsions

Allium roseum is a wild edible plant in North Africa. In the present study, the effect of freeze‐drying on the phenolic profile, the antioxidant, and the cytotoxic properties of this plant is investigated for the first time. Furthermore, this is the first research that studies its ability to preserve the stability of emulsions. We found that water extract prepared from freeze‐dried leaves (FDL) contains higher amount of phenolic compounds than the extract prepared from fresh leaves (FL) and therefore the most important antioxidant power. FDL extract is more cytotoxic on K562, MCF‐7, and Caco‐2 cancer cells. Chromatographic analyses identified kæmpferol and luteolin‐7‐o‐glucoside as the major phenolic compounds. Finally, water extract prepared from FDL preserved the physical stability of W/O emulsion at 4°C and room temperature over 30 days. It also protects those emulsions from the production of free radicals at the same …

Authors

Abdelbasset Boubakri,Hanen Najjaa,Hanane Maghrebi,Abdelkarim Ben Arfa,Marcos Antonio Das Neves,Hiroko Isoda,Mitsutoshi Nakajima,Mohamed Neffati

Journal

Journal of Food Processing and Preservation

Published Date

2021

Phenolic composition of some Tunisian medicinal plants associated with anti-proliferative effect on human breast cancer MCF-7 cells

Plants have been seen to possess the potential to be excellent biological matrices to serve as a basis for investigating the presence of promising therapeutic agents for cancer treatment. Several successful anti-cancer medicines-or their analoguesnowadays in use are plant derived and many more are under clinical trials. Under current circumstances, the purpose of this work was to test aqueous and ethanolic extracts of five aromatic and medicinal plants from arid zones on some tumor cell lines. These plants, Cymbopogon schoenanthus (L.) Spreng, Crithmum maritimum (L.) Spreng, Hammada scoparia (Pomel) Iljin, Retama raetam (Forssk.) and Zizyphus lotus (L.) Desf., widely used in Tunisian ethnomedicine, were assessed for their phenolic compounds, antioxidants and anticancer activities in aqueous and ethanol extracts. Total polyphenols, flavonoid and tannin contents were determined colorimetrically and some of these molecules were identified using RP-HPLC. A significant difference on phenolic contents and composition were found among the investigated plants. Cymbopogon schoenanthus was the richest in phenolic compounds (approx. 72%) with quercetine-3-o-rhamnoside (approx. 33%) as main contributor. For all the tested plants, the highest antioxidant capacity was detected in the ethanolic extracts rather than in the aqueous ones. The highest antiproliferative potential was observed for the ethanolic extracts. Hammada scoparia, Retama raetam and Zizyphus lotus exhibited important antiproliferative effect that reached 67% at a 1% extract concentration. Taken together, the present study supports the potential development of …

Authors

Hanen Najjaa,Ben Arfa Abdelkarim,Enrico Doria,Abdelbasset Boubakri,Najla Trabelsi,Hanen Falleh,Hajer Tlili,Mohamed Neffati

Journal

The EuroBiotech Journal

Published Date

2020

Allium roseum L. extract inhibits amyloid beta aggregation and toxicity involved in Alzheimer’s disease

Allium roseum is an important medicinal and aromatic plant, specific to the North African flora and a rich source of important nutrients and bioactive molecules including flavonoids and organosulfur compounds whose biological activities and pharmacological properties are well known. In the present study, the inhibition of amyloid beta protein toxicity by the ethanolic extract of this plant is investigated for the first time. Preliminary biochemical analyses identified kæmpferol and luteolin-7-o-glucoside as the more abundant phenolic compounds. The effects of A. roseum extract (ARE) on aggregation and aggregate cytotoxicity of amyloid beta-42 (Aβ42), whose brain aggregates are a hallmark of Alzheimer’s disease, were investigated by biophysical (ThT assay, Dynamic light scattering and transmission electron microscopy) and cellular assays (cytotoxicity, aggregate immunolocalization, ROS measurement and intracellular Ca2+ imaging). The biophysical data suggest that ARE affects the structure of the Aβ42 peptide, inhibits its polymerization, and interferes with the path of fibrillogenesis. The data with cultured cells shows that ARE reduces Aß42 aggregate toxicity by inhibiting aggregate binding to the cell membrane and by decreasing both oxidative stress and intracellular Ca2+. Accordingly, ARE could act as a neuroprotective factor against Aβ aggregate toxicity in Alzheimer’s disease.

Authors

Abdelbasset Boubakri,Manuela Leri,Monica Bucciantini,Hanen Najjaa,Abdelkarim Ben Arfa,Massimo Stefani,Mohamed Neffati

Journal

PLoS One

Published Date

2020/9/30

Abdelbasset Boubakri FAQs

What is Abdelbasset Boubakri's h-index at Universität Bern?

The h-index of Abdelbasset Boubakri has been 4 since 2020 and 4 in total.

What are Abdelbasset Boubakri's top articles?

The articles with the titles of

Biochemical Composition and Biological Activities of Various Population of Brassica tournefortii Growing Wild in Tunisia

Effect of freeze‐drying on the antioxidant and the cytotoxic properties of Allium roseum L. and its application in stabilizing food emulsions

Phenolic composition of some Tunisian medicinal plants associated with anti-proliferative effect on human breast cancer MCF-7 cells

Allium roseum L. extract inhibits amyloid beta aggregation and toxicity involved in Alzheimer’s disease

are the top articles of Abdelbasset Boubakri at Universität Bern.

What are Abdelbasset Boubakri's research interests?

The research interests of Abdelbasset Boubakri are: Organic Chemistry, Cell and Molecuar Biology, Insect control, Food Science, Agriculture Science

What is Abdelbasset Boubakri's total number of citations?

Abdelbasset Boubakri has 99 citations in total.

What are the co-authors of Abdelbasset Boubakri?

The co-authors of Abdelbasset Boubakri are ISODA H, Monica Bucciantini, Marcos A. Neves, Manuela Verri, Enrico Doria.

    Co-Authors

    H-index: 50
    ISODA H

    ISODA H

    University of Tsukuba

    H-index: 35
    Monica Bucciantini

    Monica Bucciantini

    Università degli Studi di Firenze

    H-index: 32
    Marcos A. Neves

    Marcos A. Neves

    University of Tsukuba

    H-index: 23
    Manuela Verri

    Manuela Verri

    Università degli Studi di Pavia

    H-index: 19
    Enrico Doria

    Enrico Doria

    Università degli Studi di Pavia

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